67 documents found, page 1 of 7
Measuring Adherence to Inhaled Control Medication in Patients with Asthma: Comp...
Cachim, A; Pereira, AM; Almeida, R; Amaral, R; Alves‐Correia, M; Vieira‐Marques, P; Chaves‐Loureiro, C; Ribeiro, C; Cardia, F; Gomes, J; Vidal, CBackground: Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of share...
Study protocol for a pilot randomised controlled trial evaluating the feasibili...
Gonçalves, M; Lima, MJ; Fonseca, A; Duque, C; Costa, AR; Cruz, VTIntroduction Transient ischaemic attack (TIA) and minor stroke are frequently assumed as temporary or non-disabling events. However, evidence suggests that these patients can experience relevant impairment and functional disability. Therefore, the present study aims to evaluate the feasibility and effectiveness of a 3-month multidomain intervention programme, composed of five non-pharmacological strategies, aim...
Recording of Weathering Profile Development by Uranyl-Phosphate Minerals
Gonçalves, M; Pinto, A; Mirão, JRecording of Weathering Profile Development by Uranyl-Phosphate Minerals
Sleep patterns in childhood: a longitudinal assessment from the Generation XXI ...
Gonçalves, M; Costa, AR; Severo, M; Henriques, A; Barros, HObjective: To describe sleep-wake patterns in young children, based on sleep characteristics in early infancy and preschool ages, identifying their main sociodemographic characteristics, and to assess the association between different sleep characteristics at both ages. Method: We included 1092 children from the Generation XXI birth cohort, evaluated at six months and four years of age, by face-to-face intervie...
Insomnia and nightmare profiles during the COVID-19 pandemic in Portugal: chara...
Gonçalves, M; Henriques, A; Costa, AR; Correia, D; Severo, M; Lucas, R; Barros, H; Santos, AC; Ribeiro, AI; Rocha, A; Lopes, C; Correia, D; Ramos, EObjective/background: To describe and characterize insomnia symptoms and nightmare profiles in Portugal during the first six weeks of a national lockdown due to COVID-19. Patients/methods: An open cohort study was conducted to collect information of the general population during the first wave of SARS-CoV-2/COVID-19 pandemic in Portugal. We analyzed data from 5011 participants (≥16 years) who answered a weekly ...
An integrative approach to characterize the early phases of dimethylhydrazine-i...
Silva-Reis, Carla; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Pires, MJ; Iglesias-Aguirre, CE; Cortés-Martín, A; Selma, MV; Espín, JCThis study aimed to characterize an animal model of colorectal cancer (CRC) in the early stages of disease development. Twenty-nine male Wistar rats were divided into two control groups (CTRL1 and CTRL2), receiving EDTA–saline injections and two induced groups (CRC1 and CRC2), receiving 1,2-dimethylhydrazine (DMH) injections for seven consecutive weeks. CRC1 and CTRL1 were euthanized at the 11th week, while CRC...
Pre-neoplastic lesions associated with liver and colon responses to 1,2-dimethy...
Silva-Reis, C; Faustino-Rocha, AI; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Gama, A; Ferreira, F; Oliveira, PABackground: Oestrogen (ER) and androgen (AR) receptors play an important role in normal prostate development and are also implied in prostate cancer (PCa) development. Several studies suggested that physical activity may decrease the risk of PCa development and also changes sexual hormones and their receptors. This study aimed to evaluate the effects of physical exercise on ERα and AR expression in a rat model ...
PCV50 Automatic Classification of Electronic Health Records for a Value-Based P...
Zanotto, Bruna; Etdges, Ana Paula; Dal Bosco, Avner; Cortes, Eduardo; Vieira, Renata; Ruschel, R; Martins, S; Souza, A; Valiense, C; Viegas, FThis study presents a comparative assessment of supervised machine learning (ML) methods to capture outcomes and patients' characteristics from electronic health records (EHR). We explored automatic classification of free-text data from EHRs to support a value-based program.
Germline cdh1 g212e missense variant: Combining clinical, in vitro and in vivo ...
Figueiredo, J; Mercadillo, F; Melo, S; Barroso, A; Gonçalves, M; Díaz-Tasende, J; Carneiro, P; Robles, L; Colina, F; Ibarrola, C; Perea, JE-cadherin, encoded by CDH1, is an essential molecule for epithelial homeostasis, whose loss or aberrant expression results in disturbed cell–cell adhesion, increased cell invasion and metas-tasis. Carriers of CDH1 germline mutations have a high risk of developing diffuse gastric cancer and lobular breast cancer, associated with the cancer syndrome Hereditary Diffuse Gastric Cancer (HDGC). The ubiquitous availa...
European Respiratory Society statement on sleep apnoea, sleepiness and driving ...
Bonsignore, MR; Randerath, W; Schiza, S; Verbraecken, J; Elliott, MW; Riha, R; Barbe, F; Bouloukaki, I; Castrogiovanni, A; Deleanu, O; Gonçalves, MObstructive sleep apnoea (OSA) is highly prevalent and is a recognised risk factor for motor vehicle accidents (MVA). Effective treatment with continuous positive airway pressure has been associated with a normalisation of this increased accident risk. Thus, many jurisdictions have introduced regulations restricting the ability of OSA patients from driving until effectively treated. However, uncertainty prevail...