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The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophil...

Gonçalves, M; Lopes, C; Alégot, H; Osswald, M; Bosveld, F; Ramos, C; Richard, G; Bellaiche, Y; Mirouse, V; Morais-de-Sá, E

Cytokinesis physically separates daughter cells at the end of cell division. This step is particularly challenging for epithelial cells, which are connected to their neighbors and to the extracellular matrix by transmembrane protein complexes. To systematically evaluate the impact of the cell adhesion machinery on epithelial cytokinesis efficiency, we performed an RNAi-based modifier screen in the Drosophila fo...


Recruitment and retention in a multidomain intervention for post-TIA and minor ...

Gonçalves, M; Costa, AR; Lima, MJ; Fonseca, Â; Seco, M; Duque, C; Cruz, VT


Gender Dysphoria: Concepts, Diagnosis and Clinical Management

Alves Rodrigues, C; Marguilho, M; Ferreira, B; Nascimento, S; Nascimento, M; Cardoso, S; Silva, M; Pablo, AC; Soares, C; Fernandes, C; Gonçalves, M

Gender dysphoria is defined as a condition characterized by mental suffering associated with the incongruence between one's experienced gender and their birth-assigned sex. Gender as a construct and gender dysphoria as a condition in need of multidisciplinary intervention have developed as swiftly as their visibility in society, making it mandatory to promote the literacy and education of all healthcare profess...


Characterizing the molecular and physiological changes associated with colorect...

Silva-Reis, R; Faustino-Rocha, Ana I; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Pires, MJ; Iglesias- Aguierre, CE; Cortés-Martín, A; Selma, MV

Characterizing the molecular and physiological changes associated with colorectal cancer in wistar rats


Depressive symptoms’ trajectories since adolescence and sleep quality in early ...

Gonçalves, M; Costa, AR; Ramos, E; Henriques, A

Objectives: We aimed to estimate the association between depressive symptoms’ trajectories during adolescence and young adulthood and sleep quality in early adulthood. Methods: Data from 802 participants of the EPITeen study, evaluated at 13, 17 and 21 years of age, were analysed. Depressive symptoms were assessed using the Beck Depression Inventory-II and three trajectory classes from adolescence to adulthood ...


Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysi...

Robinson, L; Roccaldo, R; Rodrigues, D; Rodriguez Perez, MdC; Rodríguez Villamizar, LA; Rodríguez, AY; Roggenbuck, U; Rohloff, P; Rohner, F

Background: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that...


Recording of Weathering Profile Development by Uranyl-Phosphate Minerals

Gonçalves, M; Pinto, A; Mirão, J

Recording of Weathering Profile Development by Uranyl-Phosphate Minerals


Measuring Adherence to Inhaled Control Medication in Patients with Asthma: Comp...

Cachim, A; Pereira, AM; Almeida, R; Amaral, R; Alves‐Correia, M; Vieira‐Marques, P; Chaves‐Loureiro, C; Ribeiro, C; Cardia, F; Gomes, J; Vidal, C

Background: Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of share...


Sleep patterns in childhood: a longitudinal assessment from the Generation XXI ...

Gonçalves, M; Costa, AR; Severo, M; Henriques, A; Barros, H

Objective: To describe sleep-wake patterns in young children, based on sleep characteristics in early infancy and preschool ages, identifying their main sociodemographic characteristics, and to assess the association between different sleep characteristics at both ages. Method: We included 1092 children from the Generation XXI birth cohort, evaluated at six months and four years of age, by face-to-face intervie...


Study protocol for a pilot randomised controlled trial evaluating the feasibili...

Gonçalves, M; Lima, MJ; Fonseca, A; Duque, C; Costa, AR; Cruz, VT

Introduction Transient ischaemic attack (TIA) and minor stroke are frequently assumed as temporary or non-disabling events. However, evidence suggests that these patients can experience relevant impairment and functional disability. Therefore, the present study aims to evaluate the feasibility and effectiveness of a 3-month multidomain intervention programme, composed of five non-pharmacological strategies, aim...


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