6 documents found, page 1 of 1

3-Hydroxypyridin-4-one based derivatives as promising neuroprotective agents fo...

Background: Parkinson’s Disease (PD) is a multifactorial, complex and progressive neurodegenerative disease, characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta [1,2]. Several pathophysiological mechanisms are involved in PD, namely Lewy bodies formation, mitochondrial dysfunction, neuroinflammation, oxidative stress and iron accumulation within the brain [3]. Iron tr...

Commitment to exporting as an antecedent of organizational skills and firm perf...

This study proposes the role of leader’s commitment to export activities as an antecedent of specific organizational skills. In particular, this research investigates whether the leaders’ commitment to exporting affects firm performance, through the mediating effect of entrepreneurial orientation, network competence, and dynamic capabilities of a firm, using survey data collected from 976 companies in Portugal....

Texture analysis from 3D model and individual slice extraction for tuberculosis...

Tuberculosis (TB) is a dreaded bacterial infection that affects human lungs. It has been known to mankind since ancient ages. ImageCLEF 2018 Tuberculosis task proposes three challenging subtasks based on Computed Tomography (CT) scan images of patients’ lungs: multi-drug resistance (MDR) detection, tuberculosis type (TBT) classification and severity scoring (SVR). In this work, two different approaches are pres...

Classification of breast lesions using quantitative dynamic contrast enhanced-MRI

Imaging biomarkers are becoming important in both research and clinical studies. This study is focused on developing measures of tumour mean, fractal dimension, homogeneity, energy, skewness and kurtosis that reflect the values of the pharmacokinetic (PK) parameters within the breast tumours, evaluate those using clinical data and in- vestigate their feasibility as a biomarker to discriminate malign from benign...

Photodynamic Antimicrobial Chemotherapy for Root Canal System Asepsis: A Narrat...

Aim. The aim of this comprehensive literature review was to address the question: Does photodynamic therapy (PDT) improve root canal disinfection through significant bacterial reduction in the root canal system? Methodology. A comprehensive narrative literature review was performed to compare PDT effect with sodium hypochlorite as the comparative classical irrigant. Two reviewers independently conducted literat...

Filling the map for antimicrobial resistance in sub- Saharan Africa ampicillin ...