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The interplay between HPV, other sexually transmissible infections and genital ...
Gonçalves Nobre, José Guilherme; Matos, Andreia; Carreira, Mariana; Santos, Ana Carolina; Veiga, Luisa Carvalho; Ginete, Catarina; Brito, MiguelBackground: The importance of Cervicovaginal Microbiota in protecting against infections (such as HPV) is already well established, namely through Lactobacillus spp., as well as the mechanism through which HPV leads to Cervical Neoplasia. However, it is not possible to classify HPV as a complete carcinogen. Thus, the importance of exploring Cervicovaginal dysbiosis with the intention of deciphering this interac...
Impact of the COVID-19 pandemic on breast cancer management in Portugal: a cros...
Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; Fernandes, João Paulo; Batista, Marta Vaz; Simas, Ana; Sales, Carolina; Gouveia, HelenaIntroduction: Cancer care providers have faced many challenges in delivering safe care for patients during the COVID-19 pandemic. This cross-sectional survey-based study investigated the impact of the pandemic on clinical practices of Portuguese medical oncologists caring for patients with breast cancer. Methods: An anonymous online survey comprising 42 questions gathered information regarding COVID-19 testing,...
Human microbiota and breast cancer : is there any relevant link? A literature r...
Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; Batista, Marta Vaz; Ribeiro, Catarina; Calle, Catarina; Cortes, Alfonso; Marhold, MaximilianBreast cancer (BC) is the most common malignancy and the second cause of cancer-specific death in women from high-income countries. Recently, gut microbiota dysbiosis emerged as a key player that may directly and/or indirectly influence development, treatment, and prognosis of BC through diverse biological processes: host cell proliferation and death, immune system function, chronic inflammation, oncogenic sign...
Cancer during pregnancy : how to handle the bioethical dilemmas? : a scoping re...
Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; de Almeida, Susana Baptista; Ferreira, Marisa Horta; Gonçalves, Inês; Braga, Sofia; Pais, DiogoEthical issues that arise during the care of a pregnant woman with cancer are challenging to physicians, policymakers, lawyers, and the bioethics community. The main purpose of this scoping review is to summarize existing literature regarding the bioethical dilemmas when a conflict arises in the maternal-fetus dyad, like the one related to cancer and pregnancy outcomes. Moreover, we illustrate the decision-maki...