4 documents found, page 1 of 1
Half-sandwich Ru(p-cymene) compounds with diphosphanes: In Vitro and In Vivo ev...
Lenis Rojas, Oscar; Robalo, M. Paula; Tomaz, Ana Isabel; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Gonçalves Teixeira, Ricardo; Marques, FernandaRuthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated as [Ru(p-cymene)(L)Cl]-[CF3SO3] (L = 1,1-bis(methylenediphenylphosphano)ethylene, 1; L = 1,1-bis(diphenylphosphano)ethylene, 2), which were characterized by elemental analysis, mass spectrometry, H-1...
Ruthenium carboranyl complexes with 2,2 '-bipyridine derivatives for potential ...
Gonçalves Teixeira, Ricardo; Marques, Fernanda; Robalo, M. Paula; Fontrodona, Xavier; Garcia, M. Helena; Geninatti Crich, Simonetta; Vinas, ClaraRuthenium complexes of carboranyl ligands offer the possibility of dual action (chemo + radiotherapy) that might result in significant clinical benefits. In that frame, we describe herein the development of ruthenium-carboranyl complexes bearing bipyridyl derivatives with the general formula [3-CO-3,3-{kappa(2)-4,4 '-R-2-2,2 '-bipy}-closo-3,1,2-RuC2B9H11] (R = CH3,RuCB1or R = CH2OH,RuCB2). Both compounds crysta...
Methyl-cyclopentadienyl ruthenium compounds with 2,2 '-bipyridine derivatives d...
Côrte-Real, Leonor; Gonçalves Teixeira, Ricardo; Girio, Patrícia; Comsa, Elisabeta; MORENO, Alexis; Nasr, Rachad; Baubichon-Cortay, HeleneNew ruthenium methyl-cyclopentadienyl compounds bearing bipyridine derivatives with the general formula [Ru(eta(5)-MeCp)(PPh3)(4,4'-R-2,2'-bpy)](+) (Ru1, R = H; Ru2, R = CH3; and Ru3, R = CH2OH) have been synthesized and characterized by spectroscopic and analytical techniques. Ru1 crystallized in the monoclinic P2(1)/c, Ru2 in the triclinic P (1) over bar, and Ru3 in the monoclinic P2(1)/n space group. In all ...
Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorina...
Gonçalves Teixeira, Ricardo; Brás, Ana Rita; Côrte-Real, Leonor; Tatikonda, Rajendhraprasad; Sanches, Anabela; Robalo, Maria Paula; Avecilla, FernandoThree new compounds have been synthesized and completely characterized by analytical and spectroscopic techniques. The new bipyridine-perfluorinated ligand L1 and the new organometallic complex [Ru(η5-MeCp)(PPh3)2Cl] (Ru1) crystalize in the centrosymmetric triclinic space group P <img height="13" border="0" style="vertical-align:bottom" width="11" alt="View the MathML source" title="View the MathML source" src=...