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(Es)Ketamine As a Treatment for Depressive Episodes With Psychotic Features: Sy...
Santos, Henrique Castro; Rodrigues, Alexandra; Machado, Tiago; Gonçalves-Pinho, Manuel; Young, Allan H; Juruena, Mario FBackground: Psychotic symptoms in depression are linked to worse outcomes, and treatment options are limited. Ketamine and esketamine are effective antidepressants, yet most studies have excluded patients with a history of psychotic symptoms. Aims: To evaluate by systematic review the efficacy and safety of ketamine and esketamine in treating patients with unipolar or bipolar depressive episodes with psychotic ...
Huntington’s Disease and Psychiatric Comorbidities: A Retrospective Study in Po...
Rocha, José; Soares, Carolina; Gonçalves-Pinho, ManuelIntroduction: Huntington’s disease is a progressive neurodegenerative disorder characterized by motor, cognitive, and behavioral symptoms. While psychiatric comorbidity is common and may influence disease outcomes, there is a lack of data on its prevalence and impact in Portugal. This study aimed to analyze the frequency and impact of a diagnosis of psychiatric comorbidities among Huntington’s disease hospitali...
Psychiatric Comorbidities in Neurologic Hospitalizations in Portugal: A Nationw...
Gonçalves-Pinho, Manuel; Martins, Bárbara; Costa, Andreia; Ribeiro, João Pedro; Freitas, Alberto; Azevedo, Elsa; Fernandes, LiaIntroduction: Psychiatric comorbidities have a significant impact on patients’ quality of life and often go undetected in neurologic practice. The aim of this study was to describe and characterize psychiatric comorbidities among patients hospitalized due to a neurologic disorder in mainland Portugal.Methods: A retrospective observational study was performed by analyzing hospitalization with a primary diagnosis...
Treatment of Anorexia Nervosa: The Importance of Disease Progression in the Pro...
Andrade, Rodrigo; Gonçalves-Pinho, Manuel; Roma-Torres, António; Brandão, IsabelIntroduction: Anorexia nervosa is a severe, usually chronic, life-threatening disease of complex etiology characterized by food restriction, overestimation of the importance of body weight and image, intense fear of weight gain and distortion of body image. Anorexia nervosa is associated with high rates of mortality, suicide and decreased quality of life. Our aim is to present an anorexia nervosa treatment prog...