2 documents found, page 1 of 1
Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved...
Chimura, Misato; Wang, Xiaowen; Jhund, Pardeep S.; Henderson, Alasdair D.; Claggett, Brian L.; Desai, Akshay S.; Fonseca, Cândida; Goncalvesova, EvaPublisher Copyright: Copyright © 2024 Chimura M et al.; Importance: Sex is associated with the clinical presentation, outcomes, and response to treatment in patients with heart failure (HF). However, little is known about the safety and efficacy of treatment with finerenone according to sex. Objective: To estimate the efficacy and safety of finerenone compared with placebo in both women and men. Design, Setting...
Effects of omecamtiv mecarbil in heart failure with reduced ejection fraction a...
Metra, Marco; Pagnesi, Matteo; Claggett, Brian L.; Díaz, Rafael; Felker, G. Michael; McMurray, John J.V.; Solomon, Scott D.; Bonderman, DianaFunding: The GALACTIC-HF trial was funded by Amgen, Cytokinetics, and Servier; AIM: Patients with heart failure with reduced ejection fraction and low systolic blood pressure (SBP) have high mortality, hospitalizations, and poorly tolerate evidence-based medical treatment. Omecamtiv mecarbil may be particularly helpful in such patients. This study examined its efficacy and tolerability in patients with SBP ≤100...