3 documents found, page 1 of 1
Metastatic cutaneous squamous cell carcinoma accounts for nearly all squamous c...
Bradley, Patrick J.; Stenman, Göran; Thompson, Lester D. R.; Skálová, Alena; Simpson, Roderick H. W.; Slootweg, Pieter J.; Franchi, AlessandroPrimary squamous cell carcinoma of the parotid gland (pSCCP) has long been recognized as a separate entity and is included in the WHO classifications of salivary gland tumors. However, it is widely accepted among head and neck pathologists that pSCCP is exceptionally rare. Yet, there are many publications describing series of pSCCP and data from SEER and other cancer register databases indicate erroneously an i...
Molecularly defined sinonasal malignancies: an overview with focus on the curre...
Skálová, Alena; Agaimy, Abbas; Bradova, Martina; Poorten, Vincent Vander; Hanna, Ehab; Guntinas-Lichius, Orlando; Franchi, Alessandro; Hellquist, HenrikClassification of tumors of the head and neck has evolved in recent decades including a widespread application of molecular testing in tumors of the sinonasal tract, salivary glands, and soft tissues with a predilection for the head and neck. The availability of new molecular techniques has allowed for the definition of multiple novel tumor types unique to head and neck sites. Moreover, an expanding spectrum of...
Chromosome translocations, gene fusions, and their molecular consequences in pl...
Stenman, Göran; Fehr, Andre; Skálová, Alena; Vander Poorten, Vincent; Hellquist, Henrik; Mikkelsen, Lauge Hjorth; Saba, Nabil F.Salivary gland tumors are a heterogeneous group of tumors originating from the major and minor salivary glands. The pleomorphic adenoma (PA), which is the most common subtype, is a benign lesion showing a remarkable morphologic diversity and that, upon recurrence or malignant transformation, can cause significant clinical problems. Cytogenetic studies of >500 PAs have revealed a complex and recurrent pattern of...