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New insights on antibacterial mode of action of blue-light photoactivated berbe...

Gonsalves, ASC; Fernandes, JR; Saavedra, MJ; Guimaraes, NM; Pereira, C; Simoes, M; Anabela Borges; Simões M

Antimicrobial photodynamic inactivation (aPDI), using photosensitisers in combination with antibiotics, is a promising multi-target strategy to address antibiotic resistance, particularly in wound infections. This study aimed to elucidate the antibacterial mode of action of combinations of berberine (Ber) or curcumin (Cur) with selected antibiotics (Ber-Ab or Cur-Ab) under blue light irradiation (420 nm) agains...


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