35 documents found, page 1 of 4
Consensus on the diagnostic and therapeutic management of chronic spontaneous u...
Criado,Paulo Ricardo; Maruta,Celina Wakisaka; Alchorne,Alice de Oliveira de Avelar; Ramos,Andréa Machado Coelho; Gontijo,BernardoAbstract: Background: Urticarias are frequent diseases, with 15% to 20% of the population presenting at least one acute episode in their lifetime. Urticaria are classified in acute ( ≤ 6 weeks) or chronic (> 6 weeks). They may be induced or spontaneous. Objectives: To verify the diagnostic and therapeutic recommendations in chronic spontaneous urticaria (CSU), according to the experience of Brazilian experts, r...
Consensus on the therapeutic management of atopic dermatitis - Brazilian Societ...
Aoki,Valeria; Lorenzini,Daniel; Orfali,Raquel Leão; Zaniboni,Mariana Colombini; Oliveira,Zilda Najjar Prado de; Rivitti-Machado,Maria CecíliaAbstract: BACKGROUND: Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with a multifactorial etiology, which includes skin barrier defects, immune dysfunction, and microbiome alterations. Atopic dermatitis is mediated by genetic, environmental, and psychological factors and requires therapeutic management that covers all the aspects of its complex pathogenesis. OBJECTIVES: The aim of...
Gnathostomiasis: an emerging infectious disease relevant to all dermatologists
Bravo,Francisco; Gontijo,BernardoAbstract: Gnathostomiasis is a parasitic infection caused by the third larval stage of nematodes of the genus Gnathostoma. The disease is endemic in some countries around the world. In the American continent, the majority of cases is concentrated in Mexico, Ecuador, and Peru. However, due to increasing traveling either at the intercontinental or intracontinental level, the disease is seen each time more frequen...
PHACE syndrome: clinical manifestations, diagnostic criteria, and management
Rotter,Anita; Samorano,Luciana Paula; Rivitti-Machado,Maria Cecília; Oliveira,Zilda Najjar Prado; Gontijo,BernardoAbstract: Infantile hemangioma can be linked to other organ malformations. In 1996, PHACE syndrome was first defined as the association of large and segmental infantile hemangioma, usually on the face, head, or cervical region, with malformations of the posterior fossa of the brain, arterial anomalies of the central nervous system, coarctation of the aorta, cardiac defects, and ocular abnormalities. Over 300 ca...
A prospective study of patients with large congenital melanocytic nevi and the ...
Viana,Ana Carolina Leite; Goulart,Eugênio Marcos Andrade; Gontijo,Bernardo; Bittencourt,Flávia VasquesAbstract: Background: Large congenital melanocytic nevus (LCMN) is considered a risk factor for melanoma, although the magnitude of this risk is controversial. Objective: To evaluate the risk of melanoma development in patients with LCMN seen at a dermatology referral center in Brazil during a twelve-year period. To the best of our knowledge, there are no published similar studies on large congenital melanocyti...
What is your diagnosis?
Panteliades,Manuela; Silva,Claudia Marcia Resende; Gontijo,BernardoAbstract: CLOVES syndrome is a rare, newly described, and relatively unknown syndrome, related to somatic mutations of the PIK3CA gene. Clinical findings include adipose tissue overgrowth, vascular malformations, epidermal nevi, scoliosis, and spinal deformities. This report deals with a characteristic phenotype case, highlighting peculiar cutaneous and radiological changes.
Efficacy and safety of a single dose pentamidine (7mg/kg) for patients with cut...
Gadelha,Ellen Priscilla Nunes; Talhari,Sinésio; Guerra,Jorge Augusto de Oliveira; Neves,Leandro Ourives; Talhari,Carolina; Gontijo,BernardoAbstract: BACKGROUND: There have been few studies on pentamidine in the Americas; and there is no consensus regarding the dose that should be applied. OBJECTIVES: To evaluate the use of pentamidine in a single dose to treat cutaneous leishmaniasis. METHODS: Clinical trial of phase II pilot study with 20 patients. Pentamidine was used at a dose of 7 mg/kg, in a single dose. Safety and adverse effects were also a...
Comorbidities and cardiovascular risk factors in patients with psoriasis
Baeta,Isabela Guimarães Ribeiro; Bittencourt,Flávia Vasques; Gontijo,Bernardo; Goulart,Eugênio Marcos AndradeBACKGROUND: Psoriasis is a chronic inflammatory disease and its pathogenesis involves an interaction between genetic, environmental, and immunological factors. Recent studies have suggested that the chronic inflammatory nature of psoriasis may predispose to an association with other inflammatory diseases, especially cardiovascular diseases and metabolic disorders. OBJECTIVES: To describe the demographic, clinic...
Epidemiological aspects of melanoma at a university hospital dermatology center...
Brandao,Flavia Vieira; Pereira,Ana Francisca Junqueira Ribeiro; Gontijo,Bernardo; Bittencourt,Flavia VasquesBACKGROUND: The incidence of melanoma has been steadily rising in past decades. Although it accounts for only 3% of all skin cancers, it is responsible for 75% of deaths. OBJECTIVE: to describe the epidemiological aspects of melanoma in a university hospital setting over a period of 20 years. METHODS: A total of 166 patients were analyzed between January 1990 and January 2010 for clinical and histological varia...
Giant congenital melanocytic nevus
Viana,Ana Carolina Leite; Gontijo,Bernardo; Bittencourt,Flávia VasquesGiant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major psychosocial impact...