4 documents found, page 1 of 1
Faster cryptococcus melanization increases virulence in experimental and human ...
Sousa, Herdson Renney de; Oliveira Júnior, Getúlio Pereira de; Frazão, Stefânia de Oliveira; Gorgonha, Kaio César de Melo; Rosa, Camila PereiraCryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work, we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates and correlated them with patient data to better understand cryptococcosis. We collected 66 C. neoformans and 19 C. gattii clinical isolates and analyzed multiple virulence phenotypes and host–pathogen interaction outcomes. C. neofo...
Laccase affects the rate of Cryptococcus neoformans nonlytic exocytosis from ma...
Frazão, Stefânia de Oliveira; Sousa, Herdson Renney de; Silva, Lenise Gonçalves da; Folha, Jéssica dos Santos; Gorgonha, Kaio César de MeloNonlytic exocytosis is a process in which previously ingested microbes are expelled from host phagocytes with the concomitant survival of both cell types. This process has been observed in the interaction of Cryptococcus spp. and other fungal cells with phagocytes as distant as mammalian, bird, and fish macrophages and ameboid predators. Despite a great amount of research dedicated to unraveling this process, t...
Autofagia não canônica em macrófagos infectados com isolados clínicos de Crypto...
Gorgonha, Kaio César de MeloDissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Pós-graduação em Medicina Tropical, 2018.; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) e Fundação de Apoio à Pesquisa do Distrito Federal (FAP-DF).; A criptococose é uma micose sistêmica causada por fungos do gênero Cryptococcus que acomete princip...
A Importância da Autofagia na Apresentação de Antígenos de Cryptococcus neoform...
Gorgonha, Kaio César de MeloBiomedicina; Submitted by Aguiar Francience (franciene.aguiar@ucb.br) on 2015-07-29T21:39:22Z No. of bitstreams: 2 license_rdf: 20618 bytes, checksum: b67ac4fa37d756ac08366dbc4e32ada7 (MD5) TCC II 1-2015 - Kaio César de Melo Gorgonha.pdf: 725697 bytes, checksum: 9227e108a8d8fa3bde955fdb89e1a8ba (MD5); Approved for entry into archive by Kelson Anthony de Menezes(kelson@ucb.br) on 2015-09-01T20:36:34Z (GMT) No. o...