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Clinician treatment choices for post-traumatic stress disorder (PTSD) - Ambassa...

Kuzman, Martina Rojnic; Padberg, Frank; Amann, Benedikt L.; Schouler-Ocak, Meryam; Bajic, Zarko; Melartin, Tarja; James, Adrian; Beezhold, Julian

Background: Considering the recently growing number of potentially traumatic events and stressors in Europe (i.e. war in Ukraine, COVID-19 pandemic, refugee waves), the European Psychiatric Association (EPA) undertook a study to investigate clinicians' treatment choices for Post-Traumatic Stress Disorder (PTSD). Results: The case-based analysis included 611 participants, who correctly classified the vignette as...


Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Diso...

Mullins, Niamh; Kang, JooEun; Campos, Adrian I; Coleman, Jonathan R I; Edwards, Alexis C; Galfalvy, Hanga; Levey, Daniel F; Lori, Adriana

Background: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) c...


The safety of agomelatine in standard medical practice in depressed patients : ...

Gorwood, Philip; Benichou, Jacques; Moore, Nicholas; Álvarez Martínez, Enric; Mertens, Joost; Aguglia, Eugenio; Figueira, Maria Luísa; Falkai, Peter

Objective: The present observational cohort study documented the safety of agomelatine in current medical practice in out-patients suffering from major depressive disorder. Method: The 6-month evolution of agomelatine-treated patients was assessed with a focus on safety (emergent adverse events, liver acceptability), severity of depression using the Clinical Global Impression Severity (CGI-S) score, and functio...


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