Background: Considering the recently growing number of potentially traumatic events and stressors in Europe (i.e. war in Ukraine, COVID-19 pandemic, refugee waves), the European Psychiatric Association (EPA) undertook a study to investigate clinicians' treatment choices for Post-Traumatic Stress Disorder (PTSD). Results: The case-based analysis included 611 participants, who correctly classified the vignette as...
Background: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) c...
Objective: The present observational cohort study documented the safety of agomelatine in current medical practice in out-patients suffering from major depressive disorder. Method: The 6-month evolution of agomelatine-treated patients was assessed with a focus on safety (emergent adverse events, liver acceptability), severity of depression using the Clinical Global Impression Severity (CGI-S) score, and functio...