12 documents found, page 1 of 2
EULAR recommendations for the management of psoriatic arthritis with pharmacolo...
Gossec, Laure; Kerschbaumer, Andreas; Ferreira, Ricardo J.O.; Aletha, Daniel; Baraliakos, Xenofon; Bertheussen, Heidi; Boehncke, Wolf-HenningObjective: New modes of action and more data on the efficacy and safety of existing drugs in psoriatic arthritis (PsA) required an update of the EULAR 2019 recommendations for the pharmacological treatment of PsA. Methods: Following EULAR standardised operating procedures, the process included a systematic literature review and a consensus meeting of 36 international experts in April 2023. Levels of evidence an...
Remission versus low disease activity as treatment targets in rheumatoid arthri...
Duarte, Cátia; Jacobs, Johannes W.G.; Ferreira, Ricardo J.O.; Welsing, Paco M.J.; Gossec, Laure; Machado, Pedro M.; van der Heijde, DésiréeObjectives: To evaluate the impact of using Simplified Disease Activity Index (SDAI)-LDA (low disease activity) versus different definitions of remission as a treatment target in established rheumatoid arthritis. Methods: A meta-epidemiological study of individual patient data from eight randomised controlled trials was performed. Four definitions of the target were considered at 6 months: (1) SDAI-LDA: SDAI≤11...
Efficacy and safety of pharmacological treatment of psoriatic arthritis: a syst...
Kerschbaumer, Andreas; Smolen, Josef S; Ferreira, Ricardo J O; Bertheussen, Heidi; Baraliakos, Xenofon; Aletaha, Daniel; McGoagle, Dennis GObjectives: To obtain an overview of recent evidence on efficacy and safety of pharmacological treatments in psoriatic arthritis (PsA). Methods: This systematic literature research (SLR) investigated the efficacy and safety of conventional synthetic (cs), biological (b) and targeted synthetic (ts) disease-modifying antirheumatic drugs (DMARDs) in patients with PsA. A systematic database search using Medline, EM...
Remission definitions guiding immunosuppressive therapy in rheumatoid arthritis...
Duarte, Cátia; Ferreira, Ricardo J. O.; Welsing, Paco M.; Jacobs, Johannes W. G.; Gossec, Laure; Machado, Pedro M.; van der Heijde, DésiréeObjective: To assess which definition of remission best predicts good radiographic outcome (GRO) and good functional outcome (GFO) in rheumatoid arthritis, focusing the updated American College of Rheumatology/European Alliance of Associations for Rheumatology criteria. Material and methods: Meta-analyses of individual patient data (IPD) from randomised controlled trials (RCTs). Six definitions of remission wer...
Correspondence on 'Re-examining remission definitions in rheumatoid arthritis: ...
Ferreira, Ricardo J. O.; Welsing, Paco M. J.; Jacobs, Johannes Wg; Gossec, Laure; Ndosi, Mwidimi; Machado, Pedro; van der Heijde, Désirée
Patient Experienced Symptom State in rheumatoid arthritis: sensitivity to chang...
Duarte, Catiá; Kvien, Tore K.; Sexton, Joe; Santos, Eduardo; de Wit, Maarten; Gossec, Laure; Silva, José A. P. daObjectives. The Patient Experienced Symptom State (PESS) is a single-question, patient-reported outcome that is validated to assess global disease impact in RA. This study addresses its sensitivity to change, and reliability. Methods. Disease activity, disease impact in the seven domains of RA Impact of Disease (RAID) and PESS were assessed in patients with RA from the NOR-DMARD registry, at two visits, 6 month...
Gender, body mass index and rheumatoid arthritis disease activity: Results from...
Jawaheer, Damini; Olsen, Jørn; Lahiff, Maureen; Forsberg, Sinikka; Lähteenmäki, Jukka; da Silveira, Ines Guimaraes; Rocha, Francisco AirtonMade available in DSpace on 2022-04-28T18:56:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-12-01; Objective: To investigate whether body mass index (BMI), as a proxy for body fat, influences rheumatoid arthritis (RA) disease activity in a gender-specific manner. Methods: Consecutive patients with RA were enrolled from 25 countries into the QUEST-RA program between 2005 and 2008. Clinical and demogra...
Gender equity in academic rheumatology, current status and potential for improv...
Ovseiko, Pavel V.; Gossec, Laure; ANDREOLI, Laura; Kiltz, Uta; van Mens, Leonieke; Hassan, Neelam; van der Leeden, Marike; Siddle, Heidi J.Funding This study was funded by the EULAR (project number: EPI 024). LCC is supported by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. PVO is supported by the NIHR Oxford Biomedical Research Centre and the European Union’s Horizon 2020 research and innovation programme (grant agreement number: 872396). HS and A-MK are supported by the NIHR Leeds Biomedical Research Centre...
Environmental and societal factors associated with COVID-19-related death in pe...
Izadi, Zara; Gianfrancesco, Milena A.; Schmajuk, Gabriela; Jacobsohn, Lindsay; Katz, Patricia; Rush, Stephanie; Ja, Clairissa; Taylor, TiffanyBackground: Differences in the distribution of individual-level clinical risk factors across regions do not fully explain the observed global disparities in COVID-19 outcomes. We aimed to investigate the associations between environmental and societal factors and country-level variations in mortality attributed to COVID-19 among people with rheumatic disease globally. Methods: In this observational study, we de...
SARS-CoV-2 outbreak in immune-mediated inflammatory diseases: the Euro-COVIMID ...
Saadoun, David; Vieira, Matheus; Vautier, Mathieu; Baraliakos, Xenofon; Andreica, Ioana; Silva, José A. P. da; Sousa, Marlene; Luís, MarianaBackground The COVID-19 pandemic has raised numerous questions among patients with immune-mediated inflammatory diseases regarding potential reciprocal effects of COVID-19 and their underlying disease, and potential effects of immunomodulatory therapy on outcomes related to COVID-19. The seroprevalence of SARS-CoV-2 and factors associated with symptomatic COVID-19 in patients with immune-mediated inflammatory d...