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Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (...

Santos,Terezinha de Jesus Teixeira; Costa,Carlos Maurício de Castro; Goubau,Patrick; Vandamme,Anne-Mieke; Desmyter,Jan; Van Dooren,Sonia

How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well...

Date: 2003   |   Origin: Oasisbr

Neuropathology of two Brazilian autopsied cases of tropical spastic paraparesis...

Castro-Costa,Carlos Maurício de; Dom,René; Carton,Herwig; Goubau,Patrick; Santos,Terezinha de Jesus Teixeira; Ferreira,Márcia Valéria Pitombeira

We report on a neuropathological analysis of two cases of TSP/HAM originating from Brazil. These two cases had, respectively, an evolution of 13 and 40 years. The main neuropathological findings consisted of spinal cord atrophy, mainly the lower thoracic cord, diffuse degeneration of the white and grey matter, rare foci of mononuclear and perivascular cuffs, and hyaline hardening of arteriolae. The supraspinal ...

Date: 2002   |   Origin: Oasisbr

Paraparesia espástica tropical nos trópicos e Brasil: análise histórica

Castro-Costa,Carlos Maurício de; Carton,Herwig; Goubau,Patrick; Figueiredo,Eberval Gadelha de; Giffoni,Silvyo David A.

A paraparesia espástica tropical (PET) é mielopatia crônica, observada predominantemente nos trópicos, recentemente descoberta ser de origem retroviral (HTLV-I). O objetivo deste estudo foi delinear a evolução histórica da sua descrição, denominações e referências etiológicas. A análise histórica revelou que essa condição teve diferentes denominações e a descoberta de sua etiologia retroviral em parte dos casos...

Date: 1994   |   Origin: Oasisbr

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