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Energy restriction, exercise and atorvastatin treatment improve endothelial dys...

Rocha, B.; Rodrigues, A. R.; Tomada, I.; Martins, M. J.; Guimarães, J. T.; Gouveia, A. M.; Almeida, H.; Neves, D.

Background: Endothelial dysfunction underlies cardiovascular disease that frequently affects aged individuals. Characterized by local decrease in nitric oxide, it results from down-regulation of endothelial nitric oxide synthase (eNOS) expression/activity. Aiming to elucidate the molecular mechanisms involved in age-related endothelial dysfunction and to unveil potential therapeutic targets, we tested how diet ...

Date: 2018   |   Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa
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