64 documents found, page 1 of 7
Anti-inflammatory and metabolic effects of lentil phenolic compounds
Geraldo, Rafaela; Gouveia, Alexandra; Neves, Delminda; Freitas, Victor; Pinto, Elisabete; Vasconcelos, Marta W.
Oat and lentil-based muffins as a functional food: enhance glycaemia control, a...
Geraldo, Rafaela; Machado, Manuela; Silva, Sara; Pinho, Simão; Gouveia, Alexandra; Neves, Delminda; Pinto, Elisabete; Pintado, ManuelaThe increased interest in functional foods has driven research into health-promoting properties. This study evaluated muffins made with 100 % oatmeal (OM) or a 50:50 lentil/oatmeal flour mix (LM) using the INFOGEST in vitro model. Analysis included starch composition, glycaemic response, cytotoxicity, and immunomodulatory effects in Caco-2 cells under basal and stimulated conditions. Digestion revealed limited ...
Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulat...
Gouveia, Alexandra
A hint for the obesity paradox and the link between obesity, perirenal adipose ...
Preza-Fernandes, J; Passos, P; Mendes-Ferreira, M; Rodrigues, AR; Gouveia, Alexandra; Fraga, A; Medeiros, R; Ribeiro, RIncreasing evidence supports a role for local fat depots in cancer outcomes. Despite the robust positive association of obesity with renal cell carcinoma (RCCa) diagnosis, increased adiposity is inversely related to RCCa oncological outcomes. Here, we sought to ascertain whether imagiologically assessed local fat depots associate with RCCa progression and survival and account for this apparent paradox. A retros...
Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulat...
Martins, AF; Neto, AC; Rodrigues, AR; Oliveira, SM; Sousa Mendes, C; Leite-Moreira, AF; Gouveia, Alexandra; Almeida, Henrique; Neves, D
Cumulative Effect of Cardiovascular Risk Factors on Regulation of AMPK/SIRT1-PG...
Pereira, AS; Gouveia, Alexandra; Tomada, N; Rodrigues, AR; D NevesCardiovascular disease risk factors (CVDRF), especially diabetes mellitus (DM), disrupt oxidative stress response. This condition underlies endothelial dysfunction, early manifested in men as erectile dysfunction. The current study is aimed at elucidating the impact of CVDRF in the oxidation responsive AMPK/SIRT1-PGC-1 alpha-SIRT3 pathway and related miRNAs in the human corpus cavernosum. Human penile tissue fr...
Characterization of α-MSH browning effect in the distinct fat depots from obese...
Salazar, M.J.; Rodrigues, A.R.; Neves, D.; Almeida, Henrique; Magalhães, J.; Gouveia, Alexandra
The melanocortins against obesity-induced adipose tissue dysfunction: role in i...
Rodrigues, A.R.; Salazar, M.J.; Neves, D.; Almeida, Henrique; Gouveia, Alexandra
Browning effect of the melanocortins among mice different adipose tissue depots
Salazar, M.J.; Rodrigues, A.R.; Neves, H.; Almeida, Henrique; Magalhães, J.; Gouveia, Alexandra
Age-related expression of TGF beta family receptors in human cumulus oophorus c...
Ribeiro, A; Freitas, C; Matos, Liliana; Gouveia, Alexandra; Gomes, F; Silva Carvalho, JLS; Almeida, HPurpose During ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reprodu...