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A investigação sobre intervenções de carreira – Estado da arte e implicações pa...

Cardoso, Paulo; Azevedo, Tiago; Alvarenga, Marco

Neste capítulo de livro faz-se uma apresentação do estado da arte sobre a investigação de processo e de resultado em aconselhamento de carreira


Intervenção em Aconselhamento de Carreira por meio da Maturidade para a Escolha...

Alvarenga, Marco; Marques, Amanda; Guilhermino, Carolina; Pollo, Tatiana; Azevedo, Tiago; Cardoso, Paulo

A Teoria Life-Span/Life Space (LSA) foi desenvolvida a partir da suposição de que assumimos diferentes papéis ao longo do ciclo vital, fundamentais para o desenvolvimento da identidade vocacional. A maturidade para a escolha profissional é um dos processos identificados no desenvolvimento de carreira. No entanto, tomar decisões sobre a carreira constitui uma tarefa complexa ao lidar com muitas dúvidas. Por este...


Exploring the Chemopreventive and Antioxidant Effects of Spearmint Leaf Hydroet...

Jesus, Tiago M.; Azevedo, Tiago; Silva-Reis, Rita; Ferreira, Tiago; Nascimento-Gonçalves, Elisabete; Medeiros, Catarina; Ferreira, João; Gama, Adelina

Human papillomavirus (HPV) is the most common sexually transmitted infectious agent and, in cases of persistent infection, may cause cancer. This study evaluated the toxicological and antitumor properties of Mentha spicata extract (MSE) in KP14HPV16 mice, which carry HPV16 oncogenes. Thirty‑three female FVB/n mice (Mus musculus), including 17 HPV‑transgenic and 16 wild‑type (WT) mice, were divided into six grou...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Effects of Ladder-Climbing Exercise on Mammary Cancer: Data from a Chemically I...

Silva, Jessica; Azevedo, Tiago; Aires, Inês; Medeiros, Catarina; Neuparth, Maria J.; Seixas, Fernanda; Ferreira, Rita; Faustino-Rocha, Ana I.

Breast cancer remains a significant global health issue, affecting both humans and companion animals, particularly female dogs and cats, where mammary tumors are among the most common cancers. Strategies to minimize the impact of this disease on patients, pet owners, and veterinary medicine are essential. This study analyses the effects of resistance training on the development of chemically induced mammary can...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Do (xeno)estrogens pose a risk to earthworms? Soy isoflavones and estradiol imp...

Azevedo, Tiago; Silva-Reis, Rita; Medeiros-Fonseca, Beatriz; Gonçalves, Mariana; Mendes, Gabriel; Roboredo, Marta; Rocha, Maria J.; Peixoto, Francisco

Understanding the impact of endocrine disruptor compounds (EDCs) across a wide range of species is crucial, given their ubiquitous presence. Although invertebrate species lack sex steroid hormone pathways, they exhibit sensitivity to EDCs, which could affect population dynamics. This study assessed reproductive endpoints and oxidative stress parameters in Eisenia fetida following exposure to estradiol and soy i...


Relation between infrared thermometry and thermal imaging for assessment of rod...

Oliveira, Paula A.; Gonçalves, Lio; Gonçalves, Mariana; Venâncio, Carlos; Azevedo, Tiago; Ribeiro, Carla; Reis, Rita; Faustino-Rocha, Ana I

Animals have been used for biomedical research since ancient times. Humane endpoints have been increasingly implemented during experimental protocols to prevent or alleviate animals’ suffering. Body temperature is an indicator of stress or anxiety. Infrared thermometer (IRT) and infrared thermal imaging camera (TIC) are commercially available for temperature measurement. This study aimed to determine mice and r...


Current views on in vivo models for breast cancer research and related drug dev...

Ferreira, Tiago; Azevedo, Tiago; Silva, Jessica; Faustino-Rocha, Ana; Oliveira, Paula A.

Introduction Animal models play a crucial role in breast cancer research, in particular mice and rats, who develop mammary tumors that closely resemble their human counterparts. These models allow the study of mechanisms behind breast carcinogenesis, as well as the efficacy and safety of new, and potentially more effective and advantageous therapeutic approaches. Understanding the advantages and disadvantages o...


The role of natural compounds in rat mammary cancer: the beneficial effects of ...

Azevedo, Tiago; Silva, J; Faustino-Rocha, Ana I; Valada, A; Anjos, L; Moura, T; Ferreira, T; Santos, M; Pires, MJ; Neuparth, MJ; Peixoto, F

Breast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, includ- ing anticancer and anti-diabetic properties. This study aimed to assess the chemopreven- tive effects of S. chamaecyparissus aqueous ex- tract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were...


The role of natural compounds in rat mammary cancer: the beneficial effects of ...

Azevedo, Tiago; Silva, Jessica; Peixoto, Francisco P.; Silvestre-Ferreira, Ana C.; Gama, Adelina; Seixas, Fernanda; Finimundy, Tiane C.; Barros, Lillian

Breast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, including anticancer and anti-diabetic properties. This study aimed to assess the chemopreventive effects of S. chamaecyparissus aqueous extract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were divid...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Supplementation of an anthocyanin-rich elderberry (Sambucus nigra L.) extract i...

Azevedo, Tiago; Ferreira, Tiago; Ferreira, João Miguel Mendes; Teixeira, Filipa; Ferreira, Diana; Silva-Reis, Rita; Neuparth, Maria João

Featured Application Due to anthocyanins' potential as colorants, this anthocyanin-rich elderberry extract presents a healthier alternative to commercially available colorants and has the potential to be used at industry level. Sambucus nigra L., popularly known as elderberry, is renowned for its amazing therapeutic properties, as well as its uses as a food source, in nutraceuticals, and in traditional medicine...

Date: 2022   |   Origin: Biblioteca Digital do IPB

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