9 documents found, page 1 of 1

Neurological Involvement in a Portuguese Cohort of IgG4-Related Disease

Introduction: Neurological involvement in immunoglobulin G4-related disease (IgG4-RD) is increasingly recognized. Its diagnosis can be challenging due to clinical mimics and difficulty in obtaining nervous system biopsies. The aim of this study was to describe a cohort of neurological IgG4-RD patients.Methods: Patients were recruited from a neuroimmunology tertiary center. Clinical, laboratory, neuroimaging and...

Hybrid Deep Brain Stimulation for Parkinson’s Disease and Dystonia Improves Sid...

Introduction: Deep brain stimulation (DBS) in movement disorders does not always achieve optimal symptomatic control. Most common issues involve suboptimal electrode positioning and target stimulation and troublesome side effects limiting the therapeutic window. Recently approved implantable pulse generators (IPG) allow for pulse widths lower than 60 μs, increasing the therapeutic window, and current steering. ...

Advantages of an Automated Method Compared With Manual Methods for the Quantifi...

Intraepidermal nerve fiber density (IENFD) measurements in skin biopsy are performed manually by 1-3 operators. To improve diagnostic accuracy and applicability in clinical practice, we developed an automated method for fast IENFD determination with low operator-dependency. Sixty skin biopsy specimens were stained with the axonal marker PGP9.5 and imaged using a widefield fluorescence microscope. IENFD was firs...

Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of ...

Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits,...

Wearable Health Technology to Quantify the Functional Impact of Peripheral Neur...

The occurrence of peripheral neuropathy (PNP) is often observed in Parkinson's disease (PD) patients with a prevalence up to 55%, leading to more prominent functional deficits. Motor assessment with mobile health technologies allows high sensitivity and accuracy and is widely adopted in PD, but scarcely used for PNP assessments. This review provides a comprehensive overview of the methodologies and the most rel...

Motor, cognitive and mobility deficits in 1000 geriatric patients : protocol of...

Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits,...

Dor na doença de Parkinson

Use of textile fibres in the reinforcement of a gypsum-cork based composite mat...

Use of textile fibres in the reinforcement of a gypsum-cork based composite mat...

The study presented herein focus on the analysis of a series of experimental tests aiming at characterizing the performance of distinct textile fibers acting as a reinforcement of a gypsum-cork composite material. Two groups of textile fibers were selected, namely synthetic fibers (glass and basalt) and natural fibers (banana and sisal). The reinforced composite material was submitted to distinct types of loadi...