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A tailor-made protocol to synthesize yolk-shell graphene-based magnetic nanopar...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.; Ferreira, Isabel C. F. R.A simple tailor-made protocol to synthesize graphene-based magnetic nanoparticles (GbMNPs) for nanomedicine is herein reported. Different GbMNPs with very distinctive physicochemical and toxicological properties were synthesized by adjusting the number of carbon precursors in the coating of superparamagnetic iron oxide nanoparticles. In vitro tests show the ability to use these GbMNPs as intelligent and on-dema...
Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia ...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Garcia-Hevia, Lorena; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.The synthesis of hydrophilic graphene-based yolk-shell magnetic nanoparticles functionalized with copolymer pluronic F-127 (GYSMNP@PF127) is herein reported to achieve an efficient multifunctional biomedical system for mild hyperthermia and stimuli-responsive drug delivery. In vitro tests revealed the extraordinary ability of GYSMNP@PF127 to act as smart stimuli-responsive multifunctional nanomedicine platform ...
Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia ...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Garcia-Hevia, Lorena; Gallo, Juan; Bañobre-López, Manuel; Dražić, GoranThe synthesis of hydrophilic graphene-based yolk-shell magnetic nanoparticles functionalized with copolymer pluronic F-127 (GYSMNP@PF127) is herein reported to achieve an efficient multifunctional biomedical system for mild hyperthermia and stimuli-responsive drug delivery. In vitro tests revealed the extraordinary ability of GYSMNP@PF127 to act as smart stimuli-responsive multifunctional nanomedicine platform fo...
A Tailor-made protocol to synthesize yolk-shell graphene-based magnetic nanopar...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.A simple tailor-made protocol to synthesize graphene-based magnetic nanoparticles (GbMNPs) for nanomedicine is herein reported. Different GbMNPs with very distinctive physicochemical and toxicological properties were synthesized by adjusting the number of carbon precursors in the coating of superparamagnetic iron oxide nanoparticles. In vitro tests show the ability to use these GbMNPs as intelligent and on-dema...
Development of stimuli-responsive graphene-based yolk-shell magnetic nanopartic...
Rodrigues, Raquel Oliveira; Baldi, Giovanni; Doumett, Saer; Bañobre-López, Manuel; Gallo, Juan; Dražić, Goran; Lima, Rui A.; Silva, AdriánMagnetic drug delivery systems have attracted much attention in the last decades due to the possibility to improve the therapeutic efficacy of anticancer drugs, by enabling instable and poorly soluble drug agents to reach tumour cells after being guided by low magnetic fields and monitored by magnetic resonance imaging (MRI) [1]. Hence, a lower amount of anticancer drug is needed and the typical side effects of...
Hydrothermal synthesis of iron oxide photo-fenton catalysts: the effect of para...
Pastrana-Martínez, Luisa; Gomes, Helder; Dražić, Goran; Faria, Joaquim; Silva, AdriánIron oxide materials were synthesized by an easy and rapid hydrothermal method using different iron precursors (FeCl3∙6H2O, Fe(NO3)3∙9H2O and K4Fe(CN)6∙3H2O), solution pHs (acid and basic) and reaction times (3 h and 6 h). The synthesized materials were thoroughly characterized by transmission electron microscopy and it was found that, depending on the synthesis conditions, iron oxide samples with crystalline o...
Photodeposition of Pt nanoparticles on TiO2–carbon xerogel composites
Gomes, Helder; Machado, Bruno; Silva, Adrián; Dražić, Goran; Faria, JoaquimCarbon xerogels synthesized from polycondensation of resorcinol with formaldehyde, having specific surface areas in the range 650 to 990 m(2) g(-1) and variable degrees of surface oxidation, are used to prepare TiO(2)-carbon xerogel composites by sol-gel methods. These composite materials are used to support Pt nanoparticles (5 wt.%) by the photodeposition technique. After a high temperature reduction treatment...
Synthesis of magnetic iron oxide nanoparticles for biomedical applications
Gomes, Cidália; Veiga, Luís; Dražić, Goran; Silva, Adrián; Gomes, HelderMagnetic iron oxide nanoparticles have been synthesized by an hydrothermal method using three different iron precursors. The yield of synthesis was determined for all samples and found to be dependent on the iron precursor, solution pH and reaction time. The synthesized nanoparticles will be characterized by transmission electron microscopy and X-ray diffraction analysis and their suitability for biomedical app...
Pt nanoparticles supported over Ce-Ti-O: the solvothermal and photochemical app...
Silva, Adrián; Machado, Bruno; Gomes, Helder; Figueiredo, José; Dražić, Goran; Faria, JoaquimCe–Ti–O supports with different Ce/Ti molar ratios were synthesized by the solvothermal method using hexadecyltrimethylammonium bromide. Pt nanoparticles were then supported by photochemical deposition. The shape, size, and structure of these materials were analyzed by high resolution transmission electron microscopy. The single CeO2 support was also prepared, consisting of agglomerated cubic particles ranging ...
TiO2-carbon xerogel composites as supports in the preparation of Pt catalysts f...
Gomes, Helder; Machado, Bruno; Silva, Adrián; Dražić, Goran; Faria, JoaquimIn the last decades, considerable efforts have been devoted to the development of heterogeneous catalysts able to perform efficient selective hydrogenation of the carbonyl function in α,β-unsaturated aldehydes, to yield the corresponding unsaturated alcohols, which are important intermediates in organic synthesis of fine chemicals for several industries, such as flavor, fragrance and pharmaceutical. Unfortunate...