8 documents found, page 1 of 1
Milk Antiviral Proteins and Derived Peptides against Zoonoses
Santos, Isabel; Silva, Mariana; Grácio, Madalena; Pedroso, Laurentina; Lima, AnaMilk is renowned for its nutritional richness but also serves as a remarkable reservoir of bioactive compounds, particularly milk proteins and their derived peptides. Recent studies have showcased several robust antiviral activities of these proteins, evidencing promising potential within zoonotic viral diseases. While several publications focus on milk’s bioactivities, antiviral peptides remain largely neglect...
The Volatile Composition and the Potential Health Benefits of Different Microal...
Grácio, Madalena; Ferreira, Joana; Steinrücken, Pia; Kleinegris, Dorinde M. M.; Sousa, Isabel; Nunes, M.C.; Raymundo, AnabelaThe use of microalgae as a food ingredient has been gaining attention in recent years due to its nutritional benefits. The main goals of this study were to (i) assess the nutritional po- tential of Chlorella vulgaris, Tetraselmis chuii, Microchloropsis gaditana, and Phaeodactylum tricornutum; (ii) evaluate their bioactive properties (antioxidant activity, total phenolic content, and α-amylase inhibitory activit...
Milk’s Bioactive Peptides: Are We Disregarding Nature’s Miracle?
Santos, Maria Isabel Silva; Grácio, Madalena; Pedroso, Laurentina; Lima, Ana Isabel GusmãoMilk has a great nutritional value duo to its amino acid composition and its fat content. However, what makes milk an excellent product for human consumption it’s the presence of bioactive sequences among their aminoacidic profile. Bioactive peptides derived from milk proteins are well known to retain many biological properties and have therapeutic effects in several health disorders. The main source of these c...
One Health Perspectives on Food Safety in Minimally Processed Vegetables and Fr...
Santos, Maria Isabel; Grácio, Madalena; Silva, Mariana Camoesas; Pedroso, Laurentina; Lima, AnaWhile food markets and food production chains are experiencing exponential growth, global attention to food safety is steadily increasing. This is particularly crucial for ready-to-eat products such as fresh-cut salads and fruits, as these items are consumed raw without prior heat treatment, making the presence of pathogenic microorganisms quite frequent. Moreover, many studies on foodborne illnesses associated...
Tuning the Bioactive Properties of Dunaliella salina Water Extracts by Ultrasou...
Ferreira, Joana P. A.; Grácio, Madalena; Sousa, Isabel; Pagarete, António; Nunes, M. Cristiana; Raymundo, Anabela(1) Background: Microalgae are promising feedstock for obtaining valuable bioactive compounds. To facilitate the release of these important biomolecules from microalgae, effective cell disruption is usually necessary, where the use of ultrasound has achieved considerable popularity as an alternative to conventional methods. (2) Methods: This paper aims to evaluate the use of ultra- sound technology in water med...
RuBisCO as a protein source for potential food applications: A review
Grácio, Madalena; Oliveira, Sabrina; Lima, Ana; Ferreira, Ricardo BoavidaRuBisCO is a complete protein, widely abundant and recognized as ideal for human consumption. Further, its biochemical composition, organoleptic and physical features mean RuBisCO has potential as a nutritionally beneficial food additive. Nonetheless, despite growing plant-based market trends, there is a lack of information about the applications of this protein. Here, we explored the biochemical features of Ru...
A proposed lectin‐mediated mechanism to explain the in Vivo antihyperglycemic a...
Grácio, Madalena; Rocha, João; Pinto, Rui; Boavida Ferreira, Ricardo; Solas, João; Eduardo‐Figueira, Maria; Sepodes, Bruno; Ribeiro, Ana CristinaExperiments conducted in vitro and in vivo, as well as clinical trials for hypoglycemic therapeutics, support the hypoglycemic properties of the lectin γ-conglutin, a Lupinus seed storage protein, by a mechanism not yet been clarified. Structural studies established that binding of γ-conglutin, in native and denatured form, to insulin occurs by a strong binding that resists rupture when 0.4 M NaCl and 0.4 M gal...
A proposed lectin-mediated mechanism to explain the in vivo antihyperglycemic a...
Grácio, Madalena; Rocha, João; Pinto, Rui; Ferreira, Ricardo Boavida; Solas, João; Eduardo-Figueira, Maria; Sepodes, Bruno; Ribeiro, Ana CristinaExperiments conducted in vitro and in vivo, as well as clinical trials for hypoglycemic therapeutics, support the hypoglycemic properties of the lectin γ-conglutin, a Lupinus seed storage protein, by a mechanism not yet been clarified. Structural studies established that binding of γ-conglutin, in native and denatured form, to insulin occurs by a strong binding that resists rupture when 0.4 M NaCl and 0.4 M gal...