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Portuguese Journal of Pediatrics a decisive tool to improve pediatric research ...

Graça, André M.

The manuscript does not include an abstract


Congenital Leukemia: A Rare Cause of Blueberry Muffin Rash

Curado, Ana Dias; Palha, Maria João; Rodrigues, Márcia; Graça, André M.; Abrantes, Margarida

Congenital leukemia is an extremely rare disease occurring within the first 28 days of life. The disease prognosis is poor with high mortality rates. We describe a case of congenital acute monocytic leukemia in a female infant whose disease underwent rapid progression and culminated in death due to multiple organ failure. Our patient presented at birth with leukemia cutis, hepatomegaly, and abnormal neurologica...


Use of Therapeutic Hypothermia in Sudden Unexpected Postnatal Collapse: A Retro...

Brito, Sara; Sampaio, Isabel; Dinis, Alexandra; Proença, Elisa; Vilan, Ana; Soares, Eunice; Pinto, Filomena; Tomé, Teresa; Graça, André M.

Introduction: Sudden and unexpected postnatal collapse is a rare event with potentially dramatic consequences. Intervention approaches are limited, but hypothermia has been considered after postnatal collapse. The aim of this study was to analyse sudden and unexpected postnatal collapse cases that underwent therapeutic hypothermia in the five Portuguese hypothermia centres. Material and methods: In this multice...


Use of Therapeutic Hypothermia in Sudden Unexpected Postnatal Collapse: A Retro...

Brito, Sara; Sampaio, Isabel; Dinis, Alexandra; Proença, Elisa; Vilan, Ana; Soares, Eunice; Pinto, Filomena; Tomé, Teresa; Graça, André M.

Introduction: Sudden and unexpected postnatal collapse is a rare event with potentially dramatic consequences. Intervention approaches are limited, but hypothermia has been considered after postnatal collapse. The aim of this study was to analyse sudden and unexpected postnatal collapse cases that underwent therapeutic hypothermia in the five Portuguese hypothermia centres.Material and Methods: In this multicen...

Date: 2021   |   Origin: Acta Médica Portuguesa

Recovery of Head Circumference Z-Score in Healthy Very Preterm Infants at Term-...

Oliveira, Joana A.; Sousa, Rodrigo; Graça, André M.

Introduction: Head circumference is widely used as a marker of brain growth in very preterm infants (VPT). We aimed to evaluate the progression of head circumference (HC), extra-cerebral space (ECS) and estimated brain volume (EBV) of VPT between birth and term equivalent age (TEA) in comparison to term-born controls. Methods: We assessed prospectively a cohort of infants born at ≤32 weeks gestation and term co...


Morbidity in Prematurity Associated with Fetal Growth Restriction: Experience o...

Silva, Noémia Rosado da; Oliveira, Joana; Berenguer, Alberto; Graça, André M.; Abrantes, Margarida; Moniz, Carlos

Introduction: Prematurity and low birth weight have been associated with increased neonatal morbidity and mortality. This study aimed to evaluate possible risk factors for prematurity associated with fetal growth restriction and being small for gestational age and to determine the incidence of morbidity in these two groups of infants.Material and Methods: Retrospective case-control study of newborns with gestat...

Date: 2018   |   Origin: Acta Médica Portuguesa

Dose de Fenobarbital Durante a Hipotermia Induzida - Deveremos Mudar a Nossa Pr...

Graça, André M.; Fernandes, Sónia; Sampaio, Isabel; Moniz, Carlos; Machado, Maria do Céu

Introdução: O fenobarbital é um fármaco anticonvulsivante de primeira linha nas convulsões neonatais. No entanto, durante o tratamento com hipotermia induzida, têm vindo a ser levantadas preocupações com os níveis séricos obtidos devido a alterações na farmacocinética. O objetivo do presente estudo foi a avaliação dos níveis de fenobarbital em recém-nascidos tratados com hipotermia após terem sido tratados com ...


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