8 documents found, page 1 of 1
Transabdominal and Transperineal Ultrasound vs Routine Care Before Instrumental...
Barros, J; Afonso, M; Martins1, AT; Carita, A; Clode, N; Ayres-de-Campos, D; Graça, LIntroduction: The role of intrapartum ultrasound as an ancillary method to instrumental vaginal delivery is yet to be determined. This study aimed to compare the use of transabdominal and transperineal ultrasound with routine clinical care before performing an instrumental vaginal delivery, regarding the incidence of adverse maternal and neonatal outcomes. Material and methods: A randomized controlled trial was...
Immunophenotype of gastric tumors unveils a pleiotropic role of regulatory t ce...
Rocha, S; Basto, AP; Ijsselsteijn, ME; Teles, SP; Azevedo, MM; Gonçalves, G; Gullo, I; Almeida, GM; Maqueda, JJ; Oliveira, MI; Carneiro, F; Barata, JTGastric cancer (GC) patients display increased regulatory T cell (Tregs) numbers in peripheral blood and among tumor-infiltrating lymphocytes. Nevertheless, the role of Tregs in GC progression remains controversial. Here, we sought to explore the impact of Tregs in GCs with distinct histology, and whether Tregs can directly influence tumor cell behavior and GC develop-ment. We performed a comprehensive immunoph...
Immunoglobulin-induced aseptic meningitis: A case report
Graça, L; Alves, J; Nuak, J; Sarmento, ABackground: Immunoglobulin associated meningitis is a rare disease that mimics infectious meningitis. This is, to our knowledge, the first case of Immunoglobulin-associated meningitis described in a patient with Systemic Lupus Erythematosus and hypogammaglobulinemia secondary to Rituximab. Case presentation: A 46-year-old female with a past medical history of Systemic Lupus Erythematosus, presented with meningi...
Breech Presentation: Vaginal Versus Cesarean Delivery, Which Intervention Leads...
Fonseca, A; Silva, R; Rato, I; Neves, AR; Peixoto, C; Ferraz, Z; Ramalho, I; Carocha, A; Félix, N; Valdoleiros, S; Galvão, A; Gonçalves, D; Curado, JINTRODUCTION: The best route of delivery for the term breech fetus is still controversial. We aim to compare maternal and neonatal outcomes between vaginal and cesarean term breech deliveries. MATERIAL AND METHODS: Multicentric retrospective cohort study of singleton term breech fetuses delivered vaginally or by elective cesarean section from January 2012 - October 2014. Primary outcomes were maternal and neona...
Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse mod...
Raposo, BR; Rodrigues-Santos, P; Carvalheiro, H; Água-Doce, AM; Carvalho, L; Pereira da Silva, JA; Graça, L; Souto-Carneiro, MMOBJECTIVE: CD8+ T cells are part of the T cell pool infiltrating the synovium in rheumatoid arthritis (RA). However, their role in the pathogenesis of RA has not been fully delineated. Using the K/BxN mouse model of spontaneous chronic arthritis, which shares many similarities with RA, we studied the potential of CD8+ T cell depletion with monoclonal antibodies (mAb) to stop and reverse the progression of exper...
A Saúde Pública e as respostas sociais (e inteligentes) às crises : editorial
Graça, L
Continuidade e mudança : para uma (re)nova(da) Revista Portuguesa de Saúde Públ...
Graça, L; Uva, A S
Relationship between the Steuart resistance index of the umbilical artery in no...
Clode, N; Marques, J P; Casal, E; Graça, LUmbilical artery Doppler velocimetry was performed at 28-32 and 36-38 weeks of gestation in a low risk population to correlate the Stuart's resistance index (Sistole/Diastole--S/D) to the weight and ponderal index of the newborn, and to determine the preditive value of S/D ratio greater than the 95 centil in the screening of newborns of weight or ponderal index lower than the 10 centil. Two hundred and eight tw...