62 documents found, page 1 of 7

Median Arcuate Ligament Syndrome (Dunbar Syndrome): The Importance of the Pre-O...

The median arcuate ligament syndrome, also known as Dunbar syndrome, is caused by stenosis of the celiac trunk due to compression by diaphragmatic fibres. The incidence of this condition remains unclear and its clinical presentation is multifarious. Diagnosis is established by angio-computed tomography to determine the extent of stenosis and the existence or not of collateral circulation. Surgical intervention ...

Ageing affects the CD4+ T cell polarization and mucosal tropism induced by TLR2...

Toll-like receptor (TLR)2 activation induces aldehyde dehydrogenase enzymes in non-mucosal dendritic cells (DCs), enabling them to metabolize vitamin A into all-trans retinoic acid, which induces the expression of mucosal-homing molecules (α4β7 and CCR9) in the activated T cells. Recently, we have shown that the simultaneous activation of non-mucosal DCs through TLR2 and TLR4 maintains such capacity while reinf...

Neoplasias cefalopancreáticas – Nova abordagem em Anatomia Patológica

Enquadramento: A duodenopancreatectomia cefálica (DPC) é uma cirurgia complexa, realizada principalmente para o tratamento de neoplasias malignas ou pré-malignas da cabeça do pâncreas, região periampular e ducto biliar distal. O correto manuseamento macroscópico das amostras de DPC é fundamental para uma avaliação histopatológica precisa, incluindo a origem do tumor, o envolvimento das margens/superfícies cirúr...

Assessing carbohydrate counting accuracy: current limitations and future direct...

Diabetes mellitus is a prevalent chronic autoimmune disease with a high impact on global health, affecting millions of adults and resulting in significant morbidity and mortality. Achieving optimal blood glucose levels is crucial for diabetes management to prevent acute and long-term complications. Carbohydrate counting (CC) is widely used by patients with type 1 diabetes to adjust prandial insulin bolus doses ...

Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 ce...

Activated CD4+ T cells located at mucosal surfaces orchestrate local effector immune mechanisms. When properly polarized, these cells contribute to block infections at early stages and may be essential to restrain the local growth of mucosal tumors, playing a critical role in host protection. How CD4+ T cells simultaneously integrate gut-homing instructions and Th polarization signals transmitted by TLR-activat...

Assessing carbohydrate counting accuracy: Current limitations and future direct...

Diabetes mellitus is a prevalent chronic autoimmune disease with a high impact on global health, affecting millions of adults and resulting in significant morbidity and mortality. Achieving optimal blood glucose levels is crucial for diabetes management to prevent acute and long-term complications. Carbohydrate counting (CC) is widely used by patients with type 1 diabetes to adjust prandial insulin bolus doses ...

Perceção dos enfermeiros das competências de tomada de decisão na triagem de Ma...

Enquadramento: A triagem de prioridades caracteriza-se por um complexo processo de tomada de decisão que visa avaliar a gravidade clínica. Objetivo: Analisar relações entre as características socioprofissionais dos enfermeiros de um serviço de urgência e a perceção das competências de tomada de decisão na triagem. Metodologia: Estudo descritivo-correlacional e transversal. A amostra foi de 47 enfermeiros e para...

“Living Together with Dementia”—A psychoeducational group programme for family ...

Purpose: To evaluate the effectiveness of the psychoeducational programme “Living together with dementia” applied to a group of family caregivers of people with dementia. Design and Methods: A quasi‐experimental study with pretest and posttest and a 4‐month follow‐up. Fifteen family caregivers of people with dementia were recruited in a community care unit in northern Portugal. Results: A positive and statistic...

Revisiting IgG antibody reactivity to epstein-barr virus in myalgic encephalomy...

Infections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). However, serological analyses of these infections remain inconclusive when comparing patients with healthy controls (HCs). In particular, it is unclear if certain EBV-derived antigens eliciting antibody responses have a biomarker potential for disease ...

Pré-Textuais