6 documents found, page 1 of 1
Ru-90@bio-MOF-1: A ruthenium(II) metallodrug occluded in porous Zn-based MOF as...
Marson Armando, Renan Augusto [UNESP]; Abuçafy, Marina Paiva [UNESP]; Graminha, Angelica Ellen; Silva, Roberto Santana daMade available in DSpace on 2021-06-25T10:24:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); One of the major challenges in the field of biomedicine is to use biocompatible carriers to achieve ef...
Antitumor and anti-Mycobacterium tuberculosis agents based on cationic rutheniu...
Santos, Edjane Rocha dos; Correa, Rodrigo de Souza; Cunha, Lucas Vinícius Pozzi da; Graminha, Angelica Ellen; Araujo, Heloisa Sobreiro Selistre deSix new complexes of Ru(II)/phenanthroline/1,4-bis(diphenylphosphino)butane containing amino acids (Glycine, L-Alanine, L-Valine, L-Tyrosine, L-Methionine or L-Tryptophan) were synthesized and characterized by IR, 31P{1H}, 13C and 1H NMR spectroscopies and cyclic voltammetry experiments. These data suggest the presence of diastereoisomers, except for the complex with glycine, amino acid that does not exhibit ch...
Complexos de Ru e Pd com bases de Schiff de ditiocarbazatos com interesse bioin...
Graminha, Angelica EllenUniversidade Federal de Minas Gerais; The present work reports the synthesis of dithiocarbazate Schiff s bases, which are versatile ligands with a significant interest due to both property and biological application. The focus of this study was the synthesis of bidentate, tridentate and tetradentate Schiff s bases derived from acetophenone, 2-acetylpyridine, benzylacetylacetone and 2,6-diacetylpyridine with S-b...
Produtos naturais e derivados, complexação com o rutênio visando aumento da ati...
Graminha, Angelica EllenConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); This work involves the synthesis and characterization of three new series of ruthenium complexes containing gallic acid and derivatives cinnamic acid and salicylic acid and derivatives, as these ligands exhibit interesting biological properties. All ligands are synthetic and natural products can be found in the daily diet. The interest in stu...
Ruthenium(II) complexes of 1,3-thiazolidine-2-thione : cytotoxicity against tum...
Correa, Rodrigo de Souza; Silva, Monize Martins da; Graminha, Angelica Ellen; Meira, Cássio Santana; Santos, Jamyle Andrade Ferreira dosThree newmixed and mononuclear Ru(II) complexes containing 1,3-thiazolidine-2-thione (tzdtH) were synthesized and characterized by spectroscopic analysis, molar conductivity, cyclic voltammetry, high-resolution electrospray ionization mass spectra and X-ray diffraction. The complexes presented unique stereochemistry and the proposed formulae are: [Ru(tzdt)(bipy)(dppb)]PF6 (1), cis-[Ru(tzdt)2(PPh3)2] (2) and tra...
Anti-mycobacterium tuberculosis and cytotoxicity activities of Ruthenium(II)/ b...
Benedicto, Augusto Vieira Lima; Correa, Rodrigo de Souza; Graminha, Angelica Ellen; Kuznetsov, Aleksey Evgenyevich; Ellena, Javier AlcidesThe [Ru(Spym)(bipy)(P–P)]PF6, [Spym = pyrimidine-2-thiolate anion; P–P = 1,2-bis(diphenylphosphino)ethane, 1,3-bis(diphenylphosphino)propane and 1,1’-bis(diphenylphosphino)ferrocene] complexes were synthesized and characterized by spectroscopic, electrochemical and elemental analysis, and by X-ray crystallography. The minimal inhibitory concentration (MIC) of the compounds against Mycobacterium tuberculosis and...