5 documents found, page 1 of 1
Linseed Oil Nanoemulsion with Pluronic® F127 Loaded with Betulinic Acid: Prepar...
Rebouças,Louhana M.; Sousa,Alexandre C. C.; Gramosa,Nilce V.; Araújo,Tamara G. de; Oliveira,Fátima de Cássia E. de; Pessoa,Cláudia do ÓThe main objective of this work was to develop a nanoemulsion based on linseed oil and betulinic acid, stabilized with Pluronic F127 and polyglycerol polyricinoleate, for anticancer applications. The nanoemulsions were synthesized by ultrasound and evaluated for in vitro cytotoxicity, particle size, polydispersity index, zeta potential, morphology, encapsulation efficiency, storage stability, rheology and in vi...
Binary Micellar Solutions of Poly(Ethylene Oxide)-Poly(Styrene Oxide) Copolymer...
Oliveira,Samira A.; Moura,Carolina L.; Cavalcante,Igor M.; Lopes,Amanda Araújo; Leal,Luzia K. A. M.; Gramosa,Nilce V.; Ribeiro,Maria E. N. P.The non-commercial copolymers E45S8, E45S17 and their mixtures with Pluronic® P123 (E21P67E21) were studied as carriers of the model drug griseofulvin. Critical micelle concentration (cmc) (dye solubilisation method), drug solubilisation capacity (Scp and Sh) determined by ultraviolet-visible (UV-Vis) spectroscopy and 1H nuclear magnetic resonance (1H NMR) and cytotoxicity (LDH activity in human neutrophils) we...
Flavonoides e terpenoides de Croton muscicarpa (Euphorbiaceae)
Barreto,Milena B.; Gomes,Clêrton L.; Freitas,João Vito B. de; Pinto,Francisco das Chagas L.; Silveira,Edilberto R.; Gramosa,Nilce V.A new sesquiterpene and twelve known compounds comprising eight flavonoids and four terpenoids, were isolated from the leaves, stems, roots and exudate of Croton muscicarpa Müll. Arg.. Their structures were identified as the terpenoids 6α-methoxy-cyperene, dammaradienol, squalene, acetyl aleuritolic acid and spathulenol, and as the flavonoids retusin, 3,7,4'-trimethoxy kaempferol, ombuine, pachipodol, kaempfero...
New flavonoids and coumarins from Platymiscium floribundum Vogel
Veloso,Pérsio A.; Pimenta,Antonia T. A.; Francisco M. de,Sousa; Falcão,Maria José C.; Gramosa,Nilce V.; Silva Junior,José Nunes daTwo new flavonoids, 3,4,10-trihydroxy-9-methoxypterocarpan and 2',4'-dihydroxy-4-methoxy-b-hydroxychacanonol, were isolated from Platymiscium floribundum, in addition to the homopterocarpin, 2',4',4-trihydroxychalcone, 7,3',5'-trihydroxyflavanone, 7,3'-dihydroxy-8,5'-dimethoxyisoflavanone, 8-hydroxy-5,6,7,-trimethoxycoumarin, 6-hydroxy-7,8-dimethoxycoumarin, 6,7,8-trimethoxycoumarin, 6,7-dimethoxycoumarin, 8-hy...
Constituintes químicos voláteis e não-voláteis de Moringa oleifera Lam., Moring...
Barreto,Milena B.; Freitas,João Vito B. de; Silveira,Edilberto R.; Bezerra,Antônio Marcos E.; Nunes,Edson P.; Gramosa,Nilce V.O estudo fitoquímico do extrato etanólico das folhas de Moringa oleifera Lam., Moringaceae, resultou no isolamento dos derivados benzilnitrilas niazirina, niazirinina e 4-hidroxifenil-acetonitrila, enquanto que das cascas dos frutos somente o octacosano foi obtido. Os óleos essenciais das folhas, flores e frutos foram analisados por cromatografia gasosa acoplada a espectrometria de massa. Os constituintes princ...