6 documents found, page 1 of 1
Novel polymeric nanoparticles as nanofertilisers for alkaline iron‐deficient co...
Pinho, Simão; Santos, Carla; Moniz, Tânia; Granja, Andreia; Sarraguça, Mafalda; Reis, Salette; Rangel, Maria; Vasconcelos, MartaBackground and aims Iron deficiency chlorosis (IDC) is a nutritional disorder impacting plants and is prevalent in calcareous alkaline soils, correspond- ing to 30% of the world’s arable land. IDC compro- mises iron uptake in crops such as soybean (Glycine max). To improve the effect of iron fertilisers, we sought to develop a nanotechnology-based interven- tion using polymeric nanoparticles (NPs) loaded with F...
New iron nanofertilizers to amend chlorosis in soybean plants
Moniz, Tânia; Pinho, Simão; Santos, Carla; Granja, Andreia; Vasconcelos, Marta; Castro, Baltazar de; Rangel, Maria; Reis, Salette
Iron nanofertilizers for the development of sustainable soybean crops
Pinho, Simão; Santos, Carla; Rangel, Maria; Vasconcelos, Marta; Granja, Andreia; Reis, Salette; Moniz, Tânia
Multifunctional targeted solid lipid nanoparticles for combined photothermal th...
Granja, Andreia; Lima-Sousa, Rita; Alves, Cátia; de Melo-Diogo, Duarte; Nunes, Cláudia; Sousa, Célia T.; Correia, I.J.; Reis, SalettePhotothermal therapy has emerged as a new promising strategy for the management of cancer, either alone or combined with other therapeutics, such as chemotherapy. The use of nanoparticles for multimodal therapy can improve treatment performance and reduce drug doses and associated side effects. Here we propose the development of a novel multifunctional nanosystem based on solid lipid nanoparticles co-loaded wit...
Nanomedicine interventions in clinical trials for the treatment of metastatic b...
Moreira, Rita; Granja, Andreia; Pinheiro, Marina; Reis, SaletteBreast cancer was responsible for the deaths of 626,679 women in 2018. After decades of research, the mortality rates remain high. While the barrier of selectively killing tumor cells is not yet overcome, the search for targeted therapeutics continues. The use of nanomedicine in cancer treatment has opened up new possibilities for more precise drug-delivery systems. This review aimed to gather information and a...
Mitoxantrone-loaded lipid nanoparticles for breast cancer therapy – quality-by-...
Granja, Andreia; Sousa, Rita Lima; Alves, Cátia; Diogo, Duarte de Melo; Pinheiro, Marina; Sousa, Célia T.; Correia, I.J.; Reis, SaletteBreast cancer is the leading cause of cancer-related deaths among women worldwide. The conventional chemotherapeutic regimens used in the treatment of this disease often lead to severe side-effects and reduced efficacy. In this study, a novel drug delivery system for the chemotherapeutic drug mitoxantrone (Mito) was developed using solid lipid nanoparticles (SLN). The production of the SLN was carried out using...