2 documents found, page 1 of 1
Recommendations for genetic testing in cardiology: Review of major internationa...
Sousa, A; Moldovan, O; Lebreiro, A; Bourbon, M; António, N; Rato, Q; Rodrigues, P; Toste, A; Gonçalves Rocha, M; Oliveira, R; Granja, S; Cruz, CIn recent years, the importance of genetic causes of cardiovascular diseases has been increasingly recognized, as the result of significant advances in molecular diagnosis techniques. This growing knowledge has enabled the identification of new phenotypes and the subclassification of clinical syndromes, impacting the therapeutic approach and genetic counseling offered to affected families. This paper describes ...
Rational Identification of a Colorectal Cancer Targeting Peptide through Phage ...
Ferreira, D; Silva, AP; Nobrega, FL; Martins, IM; Barbosa-Matos, C; Granja, S; Martins, SF; Baltazar, F; Rodrigues, LRColorectal cancer is frequently diagnosed at an advanced stage due to the absence of early clinical indicators. Hence, the identification of new targeting molecules is crucial for an early detection and development of targeted therapies. This study aimed to identify and characterize novel peptides specific for the colorectal cancer cell line RKO using a phage-displayed peptide library. After four rounds of sele...