23 documents found, page 1 of 3
Profile of drug-drug interactions and impact on the effectiveness of antiretrov...
Pontelo,Betânia Maira; Greco,Dirceu Bartolomeu; Guimarães,Nathalia Sernizon; Rotsen,Nina; Braga,Victor Alberto Rebelo; Pimentel,Pedro Henrique NogueiraABSTRACT HIV infection may be considered a chronic condition for people living with HIV with access to antiretrovirals and this has effectively increased survival. Moreover, this has also facilitated the emergence of other comorbidities increasing the risk for drug-drug interactions and polypharmacy. The profile of these interactions as well as their consequences for people living with HIV are still not complet...
Lipid accumulation product index in HIV-infected patients: a marker of cardiova...
Guimarães,Milena Maria Moreira; Greco,Dirceu Bartolomeu; Moreira,Allyson Nogueira; Guimarães,Nathalia Sernizon; Freire,Cláudia Maria VilasABSTRACT The lipid accumulation product (LAP) index is an emerging cardiovascular risk marker. We aimed to assess the accuracy of this index as a marker of cardiovascular risk in HIV-infected patients. A cross-sectional study of 133 HIV-infected patients on antiretroviral drugs and 20 non-infected controls was conducted at the outpatient clinic of a referral center of infectious and parasitic diseases. Evaluati...
Is waste collection associated with hepatitis B infection? A meta-analysis
Mol,Marcos Paulo Gomes; Cairncross,Sandy; Greco,Dirceu Bartolomeu; Heller,LeoAbstract This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientific discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were sought which had been made available on the data used by December 2013 and updated to December 2016. The quality of the included studies was assessed according ...
Trinta anos de enfrentamento à epidemia da Aids no Brasil, 1985-2015
Greco,Dirceu BartolomeuResumo A resposta brasileira à Aids foi iniciada em 1985, quando o estado brasileiro, a sociedade civil e a academia se associaram com objetivos comuns. Esta se fortaleceu com a criação do SUS em 1988, imprescindível para implementar o programa nacional de Controle das DST/AIDS, baseado nos direitos humanos, visando equidade, inclusão, integralidade e contra o preconceito e a discriminação. O Brasil foi dos pri...
Prevalência e motivos para recusar participação em pesquisa clínica
Guimarães,Nathalia Sernizon; Greco,Dirceu Bartolomeu; Fausto,Maria Arlene; Kakehasi,Adriana Maria; Guimarães,Milena Maria Moreira; Tupinambás,UnaíResumo As informações fornecidas sobre prevalência e os motivos da recusa de voluntários a participar em pesquisa científica são escassas. Este artigo objetiva descrever esses dados em coorte voltada a avaliar morbimortalidade de pessoas vivendo com HIV/aids (PVHA) a partir de estudo transversal realizado no Centro de Treinamento e Referência em Doenças Infecciosas e Parasitárias. Foram obtidas as informações: ...
Hepatitis B and C in household and health services solid waste workers
Mol,Marcos Paulo Gomes; Greco,Dirceu Bartolomeu; Cairncross,Sandy; Heller,LeoAbstract Human contact with solid waste poses biological, chemical, and physical health risks for workers involved in waste collection, transportation, and storage. The potential risk to human health resulting from contact with health services waste or household waste still sparks considerable controversy. The aim of this study was to identify the context of scientific discussions on risk/infection from the hep...
Virologic and immunologic effectiveness of darunavir-based salvage therapy in H...
Ribeiro,Karina Mota; Biscione,Fernando Martin; Westin,Mateus Rodrigues; Machado,Danielle Pessoa; Greco,Dirceu Bartolomeu; Tupinambás,UnaíBackground:Darunavir has been proven efficacious for antiretroviral-experienced HIV-1-infected patients in randomized trials. However, effectiveness of darunavir-based salvage therapy is understudied in routine care in Brazil.Methods:Retrospective cohort study of HIV-1-infected patients from three public referral centers in Belo Horizonte, who received a darunavir-based therapy between 2008 and 2010, after viro...
Contributions of culture and antimicrobial susceptibility tests to the retreatm...
Andrade,Bruno Horta; Greco,Dirceu Bartolomeu; Oliveira,Maria Tereza da Costa; Lacerda,Natalia Priscila; Correa,Ricardo de AmorimIntroduction This study evaluated the efficacy of retreatment of pulmonary tuberculosis (TB) with regard to treatment outcomes and antimicrobial susceptibility testing (ST) profiles. Methods This retrospective cohort study analyzed 144 patients treated at a referral hospital in Brazil. All of them had undergone prior treatment, were smear-positive for TB and received a standardized retreatment regimen. Fisher's...
Diretivas antecipadas de vontade: um modelo brasileiro
Dadalto,Luciana; Tupinambás,Unai; Greco,Dirceu BartolomeuO presente artigo é fruto de tese cujo objetivo geral foi propor um modelo de diretivas antecipadas de vontade para o Brasil. Para tanto, realizou-se uma revisão de literatura sobre as diretivas antecipadas nas Américas e na Europa, especialmente nos Estados Unidos da América e na Espanha, e entrevistas semiestruturadas com médicos oncologistas, intensivistas e geriatras de Belo Horizonte-MG. Percebeu-se que o ...
Slow clinical improvement after treatment initiation in Leishmania/HIV coinfect...
Souza,Guenael Freire de; Biscione,Fernando; Greco,Dirceu Bartolomeu; Rabello,AnaINTRODUCTION: In Brazil there is a large area of overlap of visceral leishmaniasis (VL) and HIV infection, which favored a increased incidence of coinfection Leishmania/HIV. METHODS: This study evaluated 65 consecutive patients with VL and their clinical response to treatment in two health care settings in Belo Horizonte, Brazil. RESULTS: At baseline, the clinical picture was similar between both groups, althou...