6 documents found, page 1 of 1
Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling, Sustaining Proliferation,...
Lemos, Isabel; Freitas-Dias, Catarina; Hipólito, Ana; JS, Ramalho; Carteni, Fabrizio; G Goncalves, Luis; MAZZOLENI, Stefano; Serpa, JacintaFunding Information: This work benefited from access to CERMAX, ITQB-NOVA, Oeiras, Portugal, with equipment funded by FCT, project AAC 01/SAICT/2016. Funding Information: The institutions are funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/202...
Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling in the ES-2 Ovarian Carcin...
Lemos, Isabel; Freitas-Dias, Catarina; Hipólito, Ana; JS, Ramalho; Carteni, Fabrizio; G Goncalves, Luis; Mazzoleni, Stefano; Serpa, JacintaFunding Information: This work benefited from access to CERMAX, ITQB-NOVA, Oeiras, Portugal, with equipment funded by FCT, project AAC 01/SAICT/2016. Funding Information: The institutions are funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/202...
Alzheimer's genetic risk factor Bin1 controls synapse vesicle exo-endocytosis i...
Barata, Mariana A.; Perdigão, Catarina; JS, Ramalho; Gomes, Edgar R.; Almeida C, GuimasFunding Information: We thank the lab members for their helpful discussions and critical review of the manuscript. We thank Dr. S. Marques and Dr. T. Pereira (NMS Platforms). This study received funding (to C.G.A.) from the Research Unit UID/04462 : iNOVA4Health-Programa de Medicina Translacional and the Associated Laboratory LS4FUTURE ( LA/P/0087/2020 ), all financially supported by Funda\u00E7\u00E3o para a C...
Glucosylated cholesterol accumulates in atherosclerotic lesions and impacts mac...
Marques, André R.A.; Ferreira, Inês; Ribeiro, Quélia; Ferraz, Maria J.; Lopes, Elizeth; Pinto, Daniela; J. Hall, Michael; JS, Ramalho; Artola, MartaAtherosclerosis can be described as a local acquired lysosomal storage disorder (LSD), resulting from the build-up of undegraded material in lysosomes. Atherosclerotic foam cells accumulate cholesterol (Chol) and glycosphingolipids (GSLs) within lysosomes. This constitutes the ideal milieu for the formation of a side product of lysosomal storage: glucosylated cholesterol (GlcChol), previously found in several L...
Lactate-coated polyurea-siRNA dendriplex
Martins, Filipa; Arada, Renata; Barros, Hélio; Matos, Paulo; JS, Ramalho; Ceña, Valentin; D. B. Bonifácio, Vasco; G Goncalves, Luis; Serpa, JacintaFunding Information: This work benefited from access to CERMAX, ITQB-NOVA, Oeiras, Portugal with equipment funded by FCT, project AAC 01/SAICT/2016. Funding Information: The institutions are funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020...
Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysos...
Lopes, Elizeth; Machado De Oliveira, Gisela; Guerreiro Simões, Catarina; Ferreira, Inês; Ramos, Cristiano Manuel Colaço; JS, RamalhoFunding Information: This work was financially supported by the FCT (Foundation for Science and Technology of the Portuguese Ministry of Science and Higher Education), Refs. 2022.01305.PTDC and 2022.03249.PTDC. The Coimbra Chemistry Centre (CQC) is supported by the FCT through projects UIDB/00313/2020 and UIDP/00313/2020. E.L. is the holder of a PhD fellowship from the FCT (2021.06265.BD). A.R.A.M. was funded b...