Made available in DSpace on 2022-04-29T08:32:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The structural fragility of monoclonal antibodies (mAbs), such as bevacizumab (BVZ), is a critical par...
Made available in DSpace on 2022-04-28T21:00:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-10-01; Tests in animals are used as models in toxicological and investigative studies. However, such tests have been considered inhumane because they can cause pain and suffering to experimental animals, while these methods can often be subjective. Protests calling for animal protection have questioned the eff...
Made available in DSpace on 2022-05-01T06:02:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Universidade Estadual Paulista; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Polyelectrolyte complexation is a technique based on interactions betw...
Made available in DSpace on 2022-05-01T08:15:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-05; Universidade Estadual Paulista; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Universidade de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Nanotechnology has been widely used in the development of polymer nanocarriers for the oral delivery of bi...
Made available in DSpace on 2022-05-01T13:41:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-05-05; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Judicious design strategies should be considered powerful tools to better control the properties of ch...
Made available in DSpace on 2021-06-25T10:47:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Ministério da Educação e Ciência; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Metronidazole (MT) is an important drug available for Helicobacter pylori infection treatment. However, in the past few years, this drug h...
Made available in DSpace on 2021-06-25T10:49:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Dexamethasone acetate (DEX), a potent anti-inflammatory, is used primarily in the treatment of inflammatory and autoimmune diseases. It was incorporated in CETETH 20 (polyoxyethylene 20 cetyl alcohol)–based liquid crystalline systems to enhance the purpose of the drug. Concomitant with the pharmaceutica...
Made available in DSpace on 2021-06-25T10:59:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-05; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The nasal route is promising for the delivery of insulin for diabetes treatment. Drug loading into del...
Made available in DSpace on 2021-06-25T11:08:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Nanostructured polyelectrolyte complexes (nano PECs) based on biopolymers are an important technological strategy to target drugs to the action and/or absorption site in a more effective way. In this work, computational studies were performe...
Made available in DSpace on 2021-06-25T11:09:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The encapsulation of nanoparticles within microparticles designed for specific delivery to the colon is a relevant strategy to avoid premature degradation or release of nanoparticles during their passage through the stomach and upper ...