58 documents found, page 1 of 6
Lanthanide-based organic salts: Synthesis, characterization, and cytotoxicity s...
Forte, Andreia; Gago, Sandra; Alves, Celso; Silva, Joana; Pedrosa, Rui; Laia, César A.T.; Marrucho, Isabel M.; Branco, Luis C.The formulation of magnetic ionic liquids (MILs) or organic salts based on lanthanides as anions has been explored. In this work, a set of choline-family-based salts, and two other, different cation families, were combined with Gadolinium(III) and Terbium(III) anions. Synthetic methodologies were previously optimized, and all organic salts were obtained as solids with melting temperatures higher than 100 °C. Th...
Valorisation of Sargassum muticum through the extraction of phenolic compounds ...
Jesus, Bárbara C.; Sáenz de Miera, Blanca; Santiago, Rubén; Martins, Alice; Pedrosa, Rui; Gonzalez-Miquel, Maria; Marrucho, Isabel M.Seaweeds are naturally abundant and spread all over the globe. They have several biologically active secondary metabolites of great interest. In this work, Sargassum muticum was the algae employed as biomass and the aim was to extract phenolic compounds (PCs) using eutectic solvents (ESs). Several betaine-based, proline-based, and choline-based ESs were tested for the extraction of PCs. All extracts were evalua...
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis,...
Forte, Andreia; Gago, Sandra; Carrott, Manuela Ribeiro; Carrott, Peter; Alves, Celso; Teodoro, Fernando; Pedrosa, Rui; Marrucho, Isabel M.Several organic salts based on the combination of two different choline derivative cations and MnCl3−, GdCl4− and TbCl4− as anions were immobilized in mesoporous silica nanoparticles (MSNs) by a two-step synthetic method. Firstly, MSNs were functionalized with choline derivative cations with chloride anions and then the metals were incorporated by the reaction of the chloride with the respective metal chloride ...
Ionic liquid-based semi-interpenetrating polymer network (sIPN) membranes for C...
Gouveia, Andreia S.L.; Bumenn, Edwin; Rohtlaid, K.; Michaud, A.; Vieira, T.M.; Delgado Alves, Vitor; Tomé, L.C.; Plesse, C.; Marrucho, Isabel M.This work explores the preparation of ionic liquid (IL)-based semi-interpenetrating polymer network (sIPN) membranes composed of poly(ethylene oxide) (PEO) network and linear nitrile butadiene rubber (NBR), incorporating up to 66 wt% of three ILs with a common cation ([C2mim]+) and different anions ([C(CN)3]–, [NTf2]– and [FSI]–). All sIPN/IL membranes were characterized by Fourier-transform infrared (FT-IR) sp...
CO2/H2 separation through poly(ionic liquid)–ionic liquid membranes: The effect...
Gouveia, Andreia S.L.; Yánez, Maria; Delgado Alves, Vitor; Palomar, J.; Moya, C.; Gorri, D.; Tomé, Liliana C.; Marrucho, Isabel M.This work presents mixed gas separation performance through PIL–IL membranes bearing pyrrolidinium-based PILs with [NTf2]– and [C(CN)3]– anions and different weight percentages of the corresponding ILs using a ternary mixture of H2, CO2 and N2 and different feed pressures ranging from 1 to 4 bar and temperatures from 20 to 80 ◦C. COSMO-RS was successfully used to understand the separation behavior of the PIL–IL...
Screening polymeric ionic liquids for chromatography-based purification of bact...
Jacinto, M.J.; Wagner, Alexandra; Sá, Inês M.; Patinha, David J.S.; Marrucho, Isabel M.; Gonçalves, João; Willson, Richard C.; Azevedo, A.M.M13 bacteriophage is a key instrument in phage display applications, as well as a possible antibacterial therapeutic agent due to its highly restrictive bacterial pathogenesis, and other applications. The traditional phage purification process is usually achieved by gradient ultracentrifugation or a combination of precipitation, centrifugation and microfiltration. These approaches easily lead to long process ti...
Supported ionic liquids as efficient materials to remove non-steroidal anti-inf...
Almeida, Hugo F.D.; Neves, Márcia C.; Trindade, Tito; Marrucho, Isabel M.; Freire, Mara G.Non-steroidal anti-inflammatory drugs (NSAIDs) are largely consumed worldwide. As a result, NSAIDs were already found in a variety of environmental aqueous samples, in concentrations ranging from ng/L to μg/L. This is due to the inability of the currently used technologies in sewage treatment plants (STPs) and wastewater treatment plants (WWTPs) to completely remove such pollutants/contaminants, thus leading to...
Supported ionic liquids as efficient materials to remove nonsteroidal anti-infl...
Almeida, Hugo F. D.; Neves, Márcia C.; Trindade, Tito; Marrucho, Isabel M.; Freire, Mara G.Non-steroidal anti-inflammatory drugs (NSAIDs) are largely consumed worldwide. As a result, NSAIDs were already found in a variety of environmental aqueous samples, in concentrations ranging from ng/L to µg/L. This is due to the inability of the currently used technologies in sewage treatment plants (STPs) and wastewater treatment plants (WWTPs) to completely remove such pollutants/contaminants, thus leading to...
Antimicrobial activities of highly bioavailable organic salts and ionic liquids...
Santos, Miguel M.; Alves, Celso; Silva, Joana; Florindo, Catarina; Petrovski, Zeljko; Marrucho, Isabel M.; Pedrosa, Rui; Branco, Luís C.As the development of novel antibiotics has been at a halt for several decades, chemically enhancing existing drugs is a very promising approach to drug development. Herein, we report the preparation of twelve organic salts and ionic liquids (OSILs) from ciprofloxacin and norfloxacin as anions with enhanced antimicrobial activity. Each one of the fluoroquinolones (FQs) was combined with six di erent organic hyd...
Supramolecular hydrogel based on a sodium deep eutectic solvent
Florindo, Catarina; Celia-Silva, Lucas G.; Martins, Luís F. G.; Branco, Luís C.; Marrucho, Isabel M.A supramolecular hydrogel based on a metal-containing deep eutectic solvent (DES) is presented here for the first time. The phase diagram of the DES-based hydrogel was drawn and its rheological properties were determined.