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A functional polymorphism in IL-36β modulates macrophage antifungal effector fu...

Gonçalves, Samuel M.; Leite, L.; de Vasconcelos, P.; Pereira, I.; Dewi, I. M. W.; Mercier, T.; Aerts, R.; Ligeiro, D.; Mendes, F.; Freitas, F.

Background: Genetic predisposition plays a major role in the development of invasive pulmonary aspergillosis (IPA). The risk and course of IPA vary significantly among patients, yet continuously new genetic mechanisms that influence individual antifungal immune responses are being discovered. While genetic variability in interleukin (IL)-1 family cytokines is recognized as an important cause of disease suscepti...

Date: 2025   |   Origin: RepositóriUM - Universidade do Minho
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