10 documents found, page 1 of 1
An immunocytochemical and in situ hybridization analysis of annexin 1 expressio...
Oliani, Sonia M. [UNESP]; Christian, Helen C.; Manston, John; Flower, Roderick J.; Perretti, MauroMade available in DSpace on 2022-04-28T19:54:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2000-01-01; The presence and localization of the anti-inflammatory protein annexin 1 (also known as lipocortin 1) in perivenular rat mast cells was investigated here. Using the rat mesenteric microvascular bed and a combination of morphologic techniques ranging from immunofluorescence to electron microscopy analyse...
Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab...
de Paula-Silva, Marina; da Rocha, Gustavo Henrique Oliveira; Broering, Milena Fronza; Queiroz, Maria Luíza; Sandri, Silvana; Loiola, Rodrigo AzevedoMade available in DSpace on 2022-04-29T08:34:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-17; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in therapeutic efficacy. Herein, we demonstrate that higher levels of colonic formyl p...
Endogenous annexin-A1 negatively regulates mast cell-mediated allergic reactions
Sinniah, Ajantha; Yazid, Samia; Bena, Stefania; Oliani, Sonia M. [UNESP]; Perretti, Mauro; Flower, Rod J.Made available in DSpace on 2020-12-12T01:06:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01; Amt der Steiermärkischen Landesregierung; Mast cell stabilizers like cromoglycate and nedocromil are mainstream treatments for ocular allergy. Biochemical studies in vitro suggest that these drugs prevent mast cell degranulation through the release of Annexin-A1 (Anx-A1) protein. However, the direct eff...
Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-is...
Piovezan, Anna P.; Batisti, Ana P.; Benevides, Maria L.A.C.S.; Turnes, Bruna L.; Martins, Daniel F.; Kanis, Luiz; Duarte, Elisa C.W.Made available in DSpace on 2018-12-11T17:11:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-05-23; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ethnopharmacological relevance Casearia sylvestris Sw. is widely used in popular medicine to treat conditions associated with pain. Aim of the study The present study investigated the influence of hydroalcoholic crude extract of Casea...
Neutrophil-derived microvesicles enter cartilage and protect the joint in infla...
Headland, Sarah E.; Jones, Hefin R.; Norling, Lucy V.; Kim, Andrew; Souza, Patricia R.; Corsiero, Elisa; Gil, Cristiane D. [UNESP]; Nerviani, AlessandraMade available in DSpace on 2018-12-11T17:00:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-11-25; Microvesicles (MVs) are emerging as a new mechanism of intercellular communication by transferring cellular lipid and protein components to target cells, yet their function in disease is only now being explored. We found that neutrophilderived MVs were increased in concentration in synovial fluid from r...
Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy
Perretti, Mauro
Melanocortin agonism as a viable strategy to control alveolar bone loss induced...
Perretti, Mauro
Distinct localization of T cell Agrin during antigen presentation - evidence fo...
Kabouridis, Panagiotis S.; Pimentel, Tatiana A.; Brancaleone, Vincenzo; D'Acquisto, Fulvio; Oliani, Sonia M. [UNESP]; Perretti, MauroMade available in DSpace on 2013-08-12T18:19:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-07-01; Made available in DSpace on 2013-09-30T18:41:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-07-01; Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:00:54Z No. of bitstreams: 0; Made available in DSpace on 2014-05-20T14:00:54Z (GMT). No. of bitstreams:...
Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis
Damazo, Amilcar S. [UNESP]; Sampaio, Andre L. F.; Nakata, Cintia M. A. G.; Flower, Roderick J.; Perretti, Mauro; Oliani, Sonia M. [UNESP]Made available in DSpace on 2013-08-28T14:07:27Z (GMT). No. of bitstreams: 1 WOS000296770000001.pdf: 4894654 bytes, checksum: 8d6e28d7ec3c8bcb4574c702fc9eb638 (MD5); Made available in DSpace on 2013-09-30T18:42:10Z (GMT). No. of bitstreams: 2 WOS000296770000001.pdf: 4894654 bytes, checksum: 8d6e28d7ec3c8bcb4574c702fc9eb638 (MD5) WOS000296770000001.pdf.txt: 55778 bytes, checksum: b43012c2ee3911107eeaf0a1f03de811...
Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in isch...
Tripatara, Pinpat; Patel, Nimesh S. A.; Brancaleone, Vincenzo; Renshaw, Derek; Rocha, Joao; Sepodes, Bruno; Mota-Filipe, Helder; Perretti, MauroThe generation of endogenous hydrogen sulphide may either-limit or or contribute to the degree of tissue injury caused by ischaemia/reperfusion injury. Here, we have attempted to characterise the endogenous hydrogen sulphide synthesis pathway and the effects of sodium hydrosulphide, a hydrogen sulphide donor, in a mouse model of renal ischaemia/reperfusion injury. Anaesthetised male C57/b mice weighing 20-25 g ...