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Anthelmintic activity of nanoencapsulated carvacryl acetate against gastrointes...

André,Weibson Paz Pinheiro; Paiva Junior,José Ribamar de; Cavalcante,Géssica Soares; Ribeiro,Wesley Lyeverton Correia; Araújo Filho,José Vilemar de

Abstract The objective of this study was to evaluate the efficacy of carvacryl acetate (CVA) and nanoencapsulated CVA (nCVA) on gastrointestinal nematodes of sheep. The CVA was nanoencapsulated with chitosan/gum arabic and the efficacy of nanoencapsulation (EE), yield, zeta potential, nanoparticle morphology and release kinetics at pH 3 and 8 were analyzed. Acute and subchronic toxicity were evaluated in rodent...

Date: 2020   |   Origin: Oasisbr

Chemical constituents of Calotropis procera latex and ultrastructural effects o...

Cavalcante,Géssica Soares; Morais,Selene Maia de; André,Weibson Paz Pinheiro; Araújo-Filho,José Vilemar de; Muniz,Celli Rodrigues

Abstract This study aimed to evaluate the anthelmintic and ultrastructural effects of Calotropis procera latex on Haemonchus contortus. C. procera latex was twice centrifuged at 10,000×g and dialyzed to obtain a fraction rich in proteins, named LP (latex protein), and at 3,000 rpm to obtain a fraction rich in secondary metabolites, named LNP (latex non-protein). Specimens of H. contortus exposed to LNP, LP and ...

Date: 2020   |   Origin: Oasisbr

Antifungal and Antioxidant Activities of Vernonia Chalybaea Mart. ex DC. Essent...

Nogueira Sobrinho,Antonio Carlos; Morais,Selene Maia de; Souza,Elnatan Bezerra de; Albuquerque,Maria Rose Jane Ribeiro; Santos,Hélcio Silva dos

Abstract: This article describes the chemical composition of Vernonia chalybaea essential oil, and investigates its antimicrobial, antioxidant and hemolytic activities. The evaluation of the antifungal activity was performed by the broth microdilution method using strains of yeasts and dermatophytic fungi. The checkerboard technique to find antimicrobial modulatory effects was performed using ketoconazole as st...

Date: 2020   |   Origin: Oasisbr

Anthelmintic activity of Eucalyptus citriodora essential oil and its major comp...

Araújo-Filho,José Vilemar de; Ribeiro,Wesley Lyeverton Correia; André,Weibson Paz Pinheiro; Cavalcante,Géssica Soares; Rios,Thays Tabosa

Abstract This study aimed to evaluate the anthelmintic activity of Eucalyptus citriodora essential oil and citronellal on sheep gastrointestinal nematodes. Essential oil composition was determined by gas chromatography mass spectrometry. The substances were evaluated in vitro using adult worm motility test (AWMT) and transmission electron microscopy (TEM). The acute toxicity test in mice and the fecal egg count...

Date: 2019   |   Origin: Oasisbr

Design of chitosan-alginate core-shell nanoparticules loaded with anacardic aci...

Paiva Filho,João Campos; Morais,Selene Maia de; Nogueira Sobrinho,Antonio Carlos; Cavalcante,Gessica Soares; Silva,Nilvan Alves da

Abstract Anacardic Acid (AA) and Cardol (CD) are the main constituents of the cashew nut shell liquid, which presented several biological activities. In this study, a 23 factorial experimental design was employed in order to evaluate the influence of the reaction conditions in the nanoencapsulation of AA and CD using Chitosan (CH), Alginate (ALG) and Arabic Gum matrices. The nanoparticles (NPs) with higher stab...

Date: 2019   |   Origin: Oasisbr

Chemical composition, antioxidant and antifungal activities of essential oils a...

Alves,Fransérgio Américo Ribeiro; Morais,Selene Maia de; Sobrinho,Antonio Carlos Nogueira; Silva,Isaac Neto Goes da; Martins,Clécio Galvão

SUMMARY Resistance to use antifungal drugs is a great concern seeking for scientists to discover new products to treat fungal infections. The aim of this study was to evaluate the antioxidant and antifungal activities of essential oils and extracts of Plectranthus grandis and Plectranthus ornatus against Trichophyton rubrum and Microsporum canis dermatophytes strains. Extracts were obtained from leaves by macer...

Date: 2018   |   Origin: Oasisbr

Anthelmintic effect of thymol and thymol acetate on sheep gastrointestinal nema...

André,Weibson Paz Pinheiro; Cavalcante,Géssica Soares; Ribeiro,Wesley Lyeverton Correia; Santos,Jessica Maria Leite dos; Macedo,Iara Tersia Freitas

Abstract Thymol is a monoterpene and acetylation form of this compound can reduce the toxicity and enhance its biological effects. The objective of this study was to evaluate the effect of thymol and thymol acetate (TA) on egg, larva and adult Haemonchus contortus and the cuticular changes, acute toxicity in mice and the efficacy on sheep gastrointestinal nematodes. In vitro tests results were analyzed by analy...

Date: 2017   |   Origin: Oasisbr

Chemical composition and bioactive compounds of grape pomace (Vitis vinifera L....

Sousa,Eldina Castro; Uchôa-Thomaz,Ana Maria Athayde; Carioca,José Osvaldo Beserra; Morais,Selene Maia de; Lima,Alessandro de; Martins,Clécio Galvão

Grape pomace (Vitis vinifera L.), Benitaka variety, grown in the semiarid region of Northeast Brazil was evaluated in relation to chemical composition, and content of minerals and functional properties. Its microbiological quality and toxic potential, using Artemia salina sp, were also investigated. The results showed that the flour obtained from these residues had below neutral pH (3.82), moisture (3.33g/100g)...

Date: 2014   |   Origin: Oasisbr

Physicochemical properties and mineral and protein content of honey samples fro...

Liberato,Maria da Conceição Tavares Cavalcanti; Morais,Selene Maia de; Magalhães,Carlos Emanuel de Carvalho; Magalhães,Islay Lima

This study evaluated the physicochemical properties and protein and mineral content of honey samples from Ceará State, Northeastern Brazil, one of the major honey exporters in the country. Nutritional importance of the minerals detected was also analyzed. Physicochemical properties were examined according to the AOAC and CAC official methods; the protein content was determined using the Bradford method, and the...

Date: 2013   |   Origin: Oasisbr

In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and La...

Macedo,Iara Tersia Freitas; Oliveira,Lorena Mayana Beserra de; Camurça-Vasconcelos,Ana Lourdes Fernandes; Ribeiro,Wesley Lyeverton Correia

Phytotherapy can be an alternative for the control of gastrointestinal parasites of small ruminants. This study evaluated the efficacy of Alpinia zerumbet, Coriandrum sativum, Tagetes minuta and Lantana camara essential oils by two in vitro assays on Haemonchus contortus, an egg hatch test (EHT) and larval development test (LDT). No effect was observed for L. camara in the EHT. A. zerumbet, C. sativum and T. mi...

Date: 2013   |   Origin: Oasisbr

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