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Ferritin heavy chain supports stability and function of the regulatory T cell l...

Wu, Qian; Carlos, Ana Rita; Braza, Faouzi; Bergman, Marie-Louise; Kitoko, Jamil Z; Bastos-Amador, Patricia; Cuadrado, Eloy; Martins, Rui

Regulatory T (TREG) cells develop via a program orchestrated by the transcription factor forkhead box protein P3 (FOXP3). Maintenance of the TREG cell lineage relies on sustained FOXP3 transcription via a mechanism involving demethylation of cytosine-phosphate-guanine (CpG)-rich elements at conserved non-coding sequences (CNS) in the FOXP3 locus. This cytosine demethylation is catalyzed by the ten–eleven transl...


Venture capital investments during Covid-19: evidence from the U.S. market

Groth, Marco

This paper studies the impact of Covid-19on the Venture Capital industry in the United States. Using a sample of 8,802 funding rounds, different univariate analyses and multiple regressions were conducted. The number of investments was not significantly affected, while companies received on average a higher round amount compared to the pre-pandemic period. This effect is mainly driven by later stage investments...


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