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North–south pathways, emerging variants, and high climate suitability character...

Miguel, Isaac; Feliz, Edwin P.; Agramonte, Robinson; Martinez, Pedro V.; Vergara, Carlos; Imbert, Yvonne; Cruz, Lucia De la; Castro, Nurys de

Background: Dengue fever remains a significant public health challenge in tropical and subtropical regions, with its transmission dynamics being influenced by both environmental factors and human mobility. The Dominican Republic, a biodiversity hotspot in the Caribbean, has experienced recurrent dengue outbreaks, yet detailed understanding of the virus's transmission pathways and the impact of climatic factors ...


Development of an amplicon-based sequencing approach in response to the global ...

Chen, Nicholas F.G.; Chaguza, Chrispin; Gagne, Luc; Doucette, Matthew; Smole, Sandra; Buzby, Erika; Hall, Joshua; Ash, Stephanie; Harrington, Rachel

The 2022 multicountry mpox outbreak concurrent with the ongoing Coronavirus Disease 2019 (COVID-19) pandemic further highlighted the need for genomic surveillance and rapid pathogen whole-genome sequencing. While metagenomic sequencing approaches have been used to sequence many of the early mpox infections, these methods are resource intensive and require samples with high viral DNA concentrations. Given the at...


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