11 documents found, page 1 of 2

Magnetic Resonance Imaging in Multiple Sclerosis: An Analysis of the Implementa...

Introduction: Magnetic resonance imaging (MRI) plays a critical role in diagnosing and monitoring people with multiple sclerosis (MS). The 2020 Portuguese Consensus on Magnetic Resonance Imaging in Multiple Sclerosis aimed to standardize MRI use. This study evaluated the implementation of the consensus in clinical practice.Methods: This is an observational, retrospective, longitudinal and multicentric study com...

Almost at Age 90, the Penfield’s Homunculus can Finally Retire...

Addressing ageism : be active in aging: study protocol

Ageism refers to stereotyping (how we think), prejudice (how we feel), and discrimination (how we act) against people based on their age. It is a serious public health issue that can negatively impact older people’s health and quality of life. The present protocol has several goals: (1) adapt the Ambivalent Ageism Scale for the general Portuguese population and healthcare professionals; (2) assess the factorial...

Inflammatory bowel disease, alpha-synuclein aggregates and Parkinson’s disease:...

The hallmark of Parkinson’s disease (PD) is the accumulation of alpha-synuclein (AS) aggregates. Prior to the central nervous system involvement, PD establishes itself in the gut as a result of the complex interplay between microbiota, the host’s immune/neural systems and increased intestinal permeability. Inflammatory Bowel Disease (IBD) patients present a higher number of AS aggregates in the intestinal wall ...

Nutritional and motor functional status in Parkinson’s disease: the NutriSPark ...

A growing body of evidence suggests that nutritional status may play an important role in the development and course of Parkinson’s disease (PD). Nutritional status is known to influence PD motor and non-motor features and is in turn influenced by disease duration and severity. A proper nutritional status assessment and intervention should be incorporated in the management and follow-up of PD patients. This stu...

Gut status in Parkinson’s disease: the GutSPark protocol

The neuropathological hallmark of Parkinson’s disease (PD) is the accumulation of alpha–synuclein (AS) aggregates. The identification of AS aggregates in gut biopsy specimens from people with PD may provide an opportunity to identify PD at a very early stage, prior to symptom onset. Changes in gut microbiota and inflammatory conditions (such as periodontitis) may be linked with PD onset/evolution. This project ...

Endoscopic gastrostomy for nutritional support in post-stroke dysphagia

Introduction: persistent dysphagia affects 15 % of stroke patients and contributes to malnutrition, aspiration, and death. This study aimed to characterize patients with post-stroke dysphagia who underwent percutaneous endoscopic gastrostomy (PEG), and to assess the impact of PEG feeding on nutritional status and outcome. Methods: an observational and retrospective study using records from patients with post-st...

Consenso Português para o Diagnóstico e Gestão Clínica da Demência com Corpos d...

A demência com corpos de Lewy é uma causa comum de demência, provocando a perda progressiva de funções cognitivas e capacidades motoras, alterações comportamentais, e perda de autonomia, com compromisso da qualidade de vida dos doentes e seus familiares. Apesar de ser a segunda causa mais frequente de demência neurodegenerativa, o diagnóstico mantém-se um desafio, devido à sua apresentação clínica heterogénea, ...

Consenso Português para o diagnóstico e gestão clínica da demência com corpos d...

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...

Consenso Português para o Diagnóstico e Gestão Clínica da Demência com Corpos d...

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...