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Host immune genetic variations influence the risk of developing acute myeloid l...
Sánchez-Maldonado, J. M.; Campa, D.; Springer, J.; Badiola, J.; Niazi, Y.; Moñiz-Díez, A.; Hernández-Mohedo, F.; González-Sierra, P.; Ter Horst, R.The purpose of this study was to conduct a two-stage case control association study including 654 acute myeloid leukaemia (AML) patients and 3477 controls ascertained through the NuCLEAR consortium to evaluate the effect of 27 immune-related single nucleotide polymorphisms (SNPs) on AML risk. In a pooled analysis of cohort studies, we found that carriers of the IL13rs1295686A/A genotype had an increased risk of...
Date: 2020
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Origin: Repositório da Universidade de Lisboa