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Polysaccharide-based nanomedicines for cancer immunotherapy: a review

Zeng, Yujun; Xiang, Yufan; Sheng, Ruilong; Tomás, Helena; Rodrigues, João; Gu, Zhongwei; Zhang, Hu; Gong, Qiyong; Luo, Kui

Cancer immunotherapy is an effective antitumor approach through activating immune systems to eradicate tumors by immunotherapeutics. However, direct administration of “naked” immunotherapeutic agents (such as nucleic acids, cytokines, adjuvants or antigens without delivery vehicles) often results in: (1) an unsatisfactory efficacy due to suboptimal pharmacokinetics; (2) strong toxic and side effects due to low ...

Date: 2021   |   Origin: DigitUMa - Repositório da Universidade da Madeira
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