2 documents found, page 1 of 1
Predicting clinical events characterizing the progression of amyotrophic latera...
Guazzo, Alessandro; Atzeni, Michele; Idi, Elena; Trescato, Isotta; Tavazzi, Erica; Longato, Enrico; Manera, Umberto; Chió, Adriano; Gromicho, MartaBackground: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that results in death within a short time span (3-5 years). One of the major challenges in treating ALS is its highly heterogeneous disease progression and the lack of effective prognostic tools to forecast it. The main aim of this study was, then, to test the feasibility of predicting relevant clinical outcomes that char...
Artificial intelligence and statistical methods for stratification and predicti...
Tavazzi, Erica; Longato, Enrico; Vettoretti, Martina; Aidos, Helena; Trescato, Isotta; Roversi, Chiara; Martins, Andreia S.; Castanho, Eduardo N.Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterised by the progressive loss of motor neurons in the brain and spinal cord. The fact that ALS's disease course is highly heterogeneous, and its determinants not fully known, combined with ALS's relatively low prevalence, renders the successful application of artificial intelligence (AI) techniques particularly arduous...