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Exploring yeast glucans for vaccine enhancement: sustainable strategies for ove...

Azevedo-Silva, João; Amorim, Manuela; Tavares-Valente, Diana; Sousa, Pedro; Mohamath, Randolph; Voigt, Emily A.; Guderian, Jeffrey A.; Kinsey, Robert

Vaccine adjuvants are important for enhancing vaccine efficacy, and although aluminium salts (Alum) are the most used, their limited ability to induce specific immune responses has spurred the search for new adjuvants. However, many adjuvants fail during product development due to manufacturability, supply, stability, or safety concerns. This work hypothesizes that protein-free yeast glucans can be used as vacc...


A recombinant leishmania antigen that stimulates human peripheral blood mononuc...

Skeiky, Yasir A. W.; Guderian, Jeffrey A.; Benson, Darin R.; Bacelar, Olivia; Carvalho Filho, Edgar Marcelino de; Kubin, Marek

p. 1527-1537; Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-09-16T17:27:13Z No. of bitstreams: 1 11111aaw.pdf: 2505648 bytes, checksum: 5976238837c366626c39bab0545a89c0 (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-03T15:02:35Z (GMT) No. of bitstreams: 1 11111aaw.pdf: 2505648 bytes, checksum: 5976238837c366626c39bab0545a89c0 (MD5); Made available...

Date: 2013   |   Origin: Oasisbr

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