22 documents found, page 1 of 3
Chemical composition and antibacterial activity of the essential oils of Blainv...
Pires, Andreza Maria L.; Albuquerque, Maria Rose Jane R.; Nunes, Edson P.; Melo, Vânia M. M.; Silveira, Edilberto R.; Pessoa, Otília Deusdênia L.The essential oils of Blainvellea rhomboidea (Asteraceae) were obtained by hydrodistillation and analyzed by GC/MS and GC/FID. Initially, the essential oil from the aerial parts was investigated. From the 18 identified components, 5-indanol (14.5%) followed by p-cymen-8-ol (10.1%), β-caryophyllene (9.6%), caryophyllene oxide (9.6%), limonene (8.6%), terpinolene (7.8%), and spathulenol (7.7%) were the major cons...
The impact of urbanization on tropical mangroves (Fortaleza, Brazil): Evidence ...
Cavalcante, Rivelino M.; Sousa, Francisco W.; Nascimento, Ronaldo F.; Silveira, Edilberto R.; Freire, George S. S.This investigation represents the first environmental diagnosis of the distribution and sources of polycyclic aromatic hydrocarbons (PAHs) in sediments from a tropical mangrove in Fortaleza, northeastern Brazil. Sediment cores from six sampling stations in the Coco´ and Ceara´ Rivers were retrieved in JuneJuly 2006 to determine 17 priority PAHs. The total PAH concentrations (SPAHs) ranged from 3.04 to 2234.76 m...
Utilização da extração em fase sólida (SPE) na determinação de hidrocarbonetos ...
Cavalcante, Rivelino M.; M. Filho, Nilton S.; Viana, Rommel B.; Oliveira, Isadora R. N.; Nascimento, Ronaldo F.; Silveira, Edilberto R.Polycyclic aromatic hydrocarbons (PAHs) are a great environmental concern mainly because of their toxic, mutagenic and carcinogenic potential. This paper reports utilization of the solid-phase extraction (SPE) technique to determine PAHs in environmental aqueous matrices. The recovery from environmental aqueous matrices fortified with PAHs varied from 63.7 to 93.1% for atmospheric liquid precipitation, from 38....
Tropane alkaloids from the stem bark of Erythroxylum bezerrae
Brito, Luana San de O.; Pinto, Francisco das Chagas L.; Moraes Filho, Manoel Odorico de; Rocha, Danilo D.; Mendoza, Maria Fernanda M.Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, P...
A proline derivative-enriched methanol fraction from Sideroxylon obtusifolium l...
Souza, Tamiris F. G.; Pierdoná, Taiana M.; Macedo, Fernanda Soares; Aquino, Pedro E. A.; Rangel, Gisele F. P.; Duarte, Rebeca S.; Silva, Lorena Mara A.It was previously demonstrated that the methanol fraction of Sideroxylon obtusifolium (MFSOL) promoted anti-inflammatory and healing activity in excisional wounds. Thus, the present work investigated the healing effects of MFSOL on human keratinocyte cells (HaCaT) and experimental burn model injuries. HaCaT cells were used to study MFSOL’s effect on cell migration and proliferation rates. Female Swiss mice were...
Biological and physical approaches on the role of piplartine (piperlongumine) i...
Henrique, Tiago; Zanon, Caroline de F. [UNESP]; Girol, Ana P. [UNESP]; Stefanini, Ana Carolina Buzzo; Contessoto, Nayara S. de A. [UNESP]Made available in DSpace on 2021-06-25T10:47:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Chronic inflammation provides a favorable microenvironment for tumorigenesis, which opens opportunities for targeting cancer development and progression. Piplartine (PL) i...
Chemical composition and anti-inflammatory activity of the decoction from leave...
Aquino, Nayara C.; Queiroz, Emerson F.; Marcourt, Laurence; Freitas, Lyara B. N.; Araújo, Emmanuel V. O.; Leal, Luzia Kalyne Almeida MoreiraMyracrodruon urundeuva (Anacardiaceae) is the scientific designation of “aroeira-do-sertão”, a tree well dispersed at the northeastern Brazil. The medicinal use of this plant is widespread throughout the rural population and the inner trunk bark decoction is used to treat cutaneous affections, urinary and respiratory diseases, and gynecological problems. “Aroeira-do-sertão” has been included in the list of nati...
Linear peptide analogues from Jatropha's orbitides promote migration of human n...
Ramalho, Suelem D. [UNESP]; Pinto, Meri Emili F. [UNESP]; Andricopulo, Renata K.; Sanches, Paulo R. S. [UNESP]; Silveira, Edilberto R.Made available in DSpace on 2020-12-12T02:32:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01. Added 1 bitstream(s) on 2021-07-15T15:07:38Z : No. of bitstreams: 1 S0103-50532019001002153.pdf: 2794919 bytes, checksum: cd2b9335294d2b610a9abbd5dc742734 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Orbitides are a class of small naturally occurring cyclic peptides with structu...
Potent nonopioid antinociceptive activity of telocinobufagin in models of acute...
Feitosa, Geissy I.M.C.; Carvalho, Isabella F.; Coelho, Edivaldo B.S.; Monteiro, Marla R.B; Medeiros, Rafael L.; Carvalho, Ellaine D.F.Introduction: In recent decades, several researches have been conducted in search of new analgesics that do not present the side effects of opioids. In this context, animal venoms contain natural painkillers that have been used for the development of new analgesics. Objective: The aims of this study were to evaluate the antinociceptive effects of telocinobufagin (TCB), a bufadienolide isolated from Rhinella jim...
Optimization of composition and obtainment parameters of biocompatible nanoemul...
Carvalho, Vanessa F. M.; Salata, Giovanna C.; Matos, Jenyffer K. R. de; Costa-Fernandez, Sandra; Chorilli, Marlus [UNESP]; Steiner, Alexandre A.Made available in DSpace on 2019-10-06T05:45:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); As a new strategy for treatment of ductal carcinoma in situ, biocompatible and bioadhesive nanoemulsio...