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The impact and characterisation of clinical diarrhoea in Intensive Care Units –...

Noronha Ferreira, Carlos; Marcelino, Paulo; Fernandes, Ana Paula; Marum, Susan

Objective: To evaluate the impact and clinically characterise patients who developed diarrhoea in an Intensive Care Unit (ICU).Design: A 1-year (2004) retrospective, case-control study.Methods: patients with an ICU stay longer than 24 hours and with enteric tube feeding, were included. Diarrhoea was defined as 3 or more loose watery stools during a 24-hour period. Patients with colectomy or ileostomy were exclu...


Hybrid or continuous renal replacement techniques for unstable haemodynamic pat...

Marcelino, Paulo; Marum, Susan; Fernandes, Ana Paula; Ribeiro, J P

Comparative study to evaluate the impact of a hybrid renal replacement technique (HRRT) vs a continuous renal replacement technique (haemodiafiltration) on hemodynamic tolerance, azotemic control, and mortality in critical care patients with acute renal failure.a 14-bed Intensive Care Unit (ICU).Two groups of patients were retrospectively compared: patients submitted to continuous renal replacement techniques (...

Date: 2007   |   Origin: Acta Médica Portuguesa

Transthoracic echocardiography for evaluation of hypotensive critically ill pat...

Marcelino, Paulo; Marum, Susan; Fernandes, Ana Paula; Lopes, Mário G

a prospective study to determine the value of transthoracic echocardiography (TTE) in assessing hypotensive patients in a medical/surgical Intensive care Unit (ICU).a 16-bed medical/surgical ICU.patients with hypotension were studied (systolic arterial pressure < 90 mmHg or mean arterial pressure < 60 mmHg, non responsive to fluid therapy in a 30-minute period). TTE was aimed to: exclude severe cardiac dysfunct...

Date: 2007   |   Origin: Acta Médica Portuguesa

Serum lactate changes and its correlation with serum liver tests in liver trans...

Machado, Mariana; Marcelino, Paulo; Ferreira, Carlos; Marum, Susan; Marques-Vidal, Pedro; Fernandes, Ana Paula

Objective: To study the correlation between serum lactate levels and complications in the immediate post-operative phase of orthotopic liver transplant (OLT). Setting: medical-surgical intensive care unit with 14 bedsDesign: retrospective case-control studyMethods: 43 patients who underwent OLT were included in the study. Twenty-three patients had a favourable evolution and constituted the control group; 20 pat...


Haemodynamic parameters obtained by transthoracic echocardiography and Swan-Gan...

Marcelino, Paulo; Germano, Nuno; Marum, Susan; Fernandes, Ana Paula; Ribeiro, Palmeiro; Lopes, Mário G

To compare the haemodynamic measurements of cardiac output (CO), central venous pressure (CVP), pulmonary capillary wedge pressure (Pw) and pulmonary artery systolic pressure (PASP), obtained by Swan-Ganz catheter and transthoracic echocardiography.Prospective study in a Medical/Surgical Intensive Care Unit (ICU). A total of 41 post liver transplant patients were enrolled. CO, CVP, Pw and PASP, were simultaneou...

Date: 2006   |   Origin: Acta Médica Portuguesa

Fluid therapy in sepsis and the role of echocardiography in evaluating dynamic ...

Marcelino, Paulo; Fernandes, Ana Paula; Marum, Susan

Internal Medicine physicians work frequently in emergency departments. In this setting we intend to review some controversial features regarding fluid therapy. Although a common practice, its side effects, specific end-points and volume are not well known. Static parameters such as pressure-derived indices are not useful guides to predict the influence of fluids on cardiac output. Dynamic parameters of fluid re...


Determinantes cardíacas do tempo de ventilação mecânica e mortalidade de doente...

Marcelino, Paulo; Germano, Nuno; Nunes, Ana Paiva; Flora, Lígia; Moleiro, Ana; Marum, Susan; Fernandes, Ana Paula

Objective: To study the influence of cardiac status on the length of mechanical ventilation, outcome and disease severity in patients admitted to an Intensive Care Unit (ICU) with exacerbation of chronic respiratory failure. Design and setting: A 30-month prospective study in a 14 bed ICU Patients and methods: Fifty nine patients were enrolled, with a mean age 74.7 +/- 9.7 years, mean length of ventilator suppo...


Mortal adverse reaction to Rifampicin – A clinical case report

Lobato de Faria, Raul; Marcelino, Paulo; Marum, Susan; Ribeiro, Joaquim

The prevalence of Mycobacterium tuberculosis infectionand the relevance of rifampicin in its treatment ledus to present the following clinical case report, whichis characterized by multi-organic failure in thecontext of an adverse reaction to rifampicin.Secondary effects to drugs deserve specialattention and, in the case of rifampicin we shouldbe specially alerted to intermittent and previoustherapy with possib...


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