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Bipolar disorder diagnostic stability: a Portuguese multicentric study

Barata, P; Godinho, F; Guedes, R; Silva ., L; Oliveira, P; Serrano, R; Oliveira, CF; Pereira, ME; Martins, B; Araújo, R; Borja-Santos, N


Five-membered iminocyclitol a-glucosidase inhibitors: Synthetic,biological scre...

Guerreiro, L; Carreiro, E; Fernandes, L; Cardote, T; Moreira, R; Caldeira, A Teresa; Guedes, R; Burke, A J

The design and synthesis of a small library of pyrrolidine iminocyclitol inhibitors with a structural similarity to 1,4-dideoxy-1,4-imino-D-arabitol (DAB-1) is reported. This library was specifically designed to gain a better insight into the mechanism of inhibition of glycosidases by polyhydroxylated pyrrolidines or iminocyclitols. Pyrrolidine-3,4-diol 15a and pyrrolidine-3,4-diol diacetate 15b had emerged as ...


Macrocyclic copper(II) complexes as superoxide scavengers

Matxain, JM; Santos, DJVAdos; Fernandes, AS; Cabral, MF; Costa, J; Castro, M; Oliveira, NG; Guedes, R


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