5 documents found, page 1 of 1
Mediterranean Diet-Based Sustainable Healthy Diet and Multicomponent Training C...
Sampaio, Joana; Pizarro, Andreia; Pinto, Joana; Oliveira, B.M.P.M.; Moreira, André; Padrão, Patrícia; Guedes de Pinho, P.; Moreira, Pedro<jats:p>Background: Diet and exercise interventions have been associated with improved body composition and physical fitness. However, evidence regarding their combined effects in older adults is scarce. This study aimed to investigate the impact of a combined 12-week Mediterranean diet-based sustainable healthy diet (SHD) and multicomponent training (MT) intervention on body composition, anthropometry, and phy...
Metabolic reprogramming of sunitinib- and pazopanib-resistant renal cell carcin...
Amaro, E.; Carvalho, M.; Bastos, M. L.; Guedes de Pinho, P.; Pinto, J.Background: Tyrosine kinase inhibitors (TKIs), such as sunitinib and pazopanib, changed the therapeutic landscape of metastatic renal cell carcinoma (RCC) [1,2]. However, TKIs resistance and disease progression within one year have been observed even in patients who initially respond to treatment [3]. Hence, understanding the metabolic mechanisms associated with TKIs resistance is of utmost importance to revers...
Effect of Hemodynamic Changes in Plasma Propofol Concentrations Associated with...
Chalo, D.; Pedrosa, S.; Amorim, Pedro; Silva, A.; Guedes de Pinho, P.; Correia, R.; Gouveia, S.; Sancho, C.Background: Anesthesia induction and maintenance with propofol can be guided by target-controlled infusion (TCI) systems using pharmacokinetic (Pk) models. Physiological variables, such as changes in cardiac output (CO), can influence propofol pharmacokinetics. Knee-chest (KC) surgical positioning can result in CO changes. Objectives: This study aimed to evaluate the relationship between propofol plasma concent...
Exploratory urinary metabolomic profiling of renal cell carcinoma using H-1 NMR...
Monteiro, M.; Barros, A.; Carvalho, M.; Pires-Luis, A. S.; Jeronimo, C.; Henrique, R.; Maria de Lourdes, B.; Gil, A.; Guedes de Pinho, P.
Madeira wine: Mechanisms of formation and impact on character
Ferreira, A. C. Silva; Silva, H. Oliveira; Machad, B. P.; Marques, C.; Albuquerque, F.; Camara, J.; Hogg, T.; Guedes de Pinho, P.