35 documents found, page 1 of 4
Computational Insights into the Interplay of Mechanical Forces in Angiogenesis
Guerra, A; Belinha, J; Salgado, CL; Monteiro, FJ; Jorge, RNThis study employs a meshless computational model to investigate the impacts of compression and traction on angiogenesis, exploring their effects on vascular endothelial growth factor (VEGF) diffusion and subsequent capillary network formation. Three distinct initial domain geometries were defined to simulate variations in endothelial cell sprouting and VEGF release. Compression and traction were applied, and t...
Radiologic-pathologic correlation of prostatic cancer extracapsular extension (...
Guerra, A; Flor-de-Lima, B; Freire, G; Lopes, A; Cassis, JRecent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular ex...
A Comprehensive Look at In Vitro Angiogenesis Image Analysis Software
Pereira, M; Pinto, J; Arteaga, B; Guerra, A; Jorge, RN; Monteiro, FJ; Salgado, CLOne of the complex challenges faced presently by tissue engineering (TE) is the development of vascularized constructs that accurately mimic the extracellular matrix (ECM) of native tissue in which they are inserted to promote vessel growth and, consequently, wound healing and tissue regeneration. TE technique is characterized by several stages, starting from the choice of cell culture and the more appropriate ...
Adjustable Gastric Banding Conversion to One Anastomosis Gastric Bypass: Data A...
Pujol-Rafols, J; Uyanik, O; Curbelo-Peña, Y; Abbas, AA; Devriendt, S; Guerra, A; Herrera, MF; Himpens, J; Pardina, E; Pouwels, S; Ramos, A; Ribeiro, RJIntroduction: One anastomosis gastric bypass (OAGB) has been proposed as a rescue technique for laparoscopic adjustable gastric banding (LAGB) poor responders. Aim: We sought to analyze, complications, mortality, and medium-term weight loss results after LAGB conversion to OAGB. Methods: Data analysis of an international multicenter database. Results: One hundred eighty-nine LAGB-to-OAGB operations were retrosp...
Association between Elevated Iodine Intake and IQ among School Children in Port...
Carvalho, IP; Peixoto, B; Caldas, JC; Costa, A; Silva, S; Moreira, B; Almeida, A; Moreira-Rosário, A; Guerra, A; Delerue-Matos, C; Sintra, D; Pestana, DThe goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...
Impact of physical activity on redox status and nitric oxide bioavailability in...
Leite-Almeida, L; Morato, M; Cosme, D; Afonso, J; Areias, JC; Guerra, A; Caldas, Afonso, A; Albino-Teixeira, A; Sousa, T; Correia-Costa, LNutritional status might contribute to variations induced by physical activity (PA) in redox status biomarkers. We investigated the influence of PA on redox status and nitric oxide (NO) production/metabolism biomarkers in nonoverweight and overweight/obese prepubertal children. We performed a cross-sectional evaluation of 313 children aged 8-9 years (163 nonoverweight, 150 overweight/obese) followed since birth...
Conversion of Adjustable Gastric Banding to Roux-en-Y Gastric Bypass in One or ...
Pujol-Rafols, J; Abbas, A; Devriendt, S; Guerra, A; Herrera, M; Himpens, J; Pardina, E; Pouwels, S; Ramos, A; Ribeiro, R; Safadi, B; Sanchez-Aguilar, HBackground: Roux-en-Y gastric bypass (RYGB) is often the preferred conversion procedure for laparoscopic adjustable gastric banding (LAGB) poor responders. However, there is controversy whether it is better to convert in one or two stages. This study aims to compare the outcomes of one and two-stage conversions of LAGB to RYGB. Methods: Retrospective review of a multicenter prospectively collected database. Dat...
Conversion of Adjustable Gastric Banding to Roux-en-Y Gastric Bypass in One or ...
Pujol-Rafols, J; Al Abbas, AI; Devriendt, S; Guerra, A; Herrera, MF; Himpens, J; Pardina, E; Pouwels, S; Ramos, A; Ribeiro, RJ; Safadi, BBackground: Roux-en-Y gastric bypass (RYGB) is often the preferred conversion procedure for laparoscopic adjustable gastric banding (LAGB) poor responders. However, there is controversy whether it is better to convert in one or two stages. This study aims to compare the outcomes of one and two-stage conversions of LAGB to RYGB. Methods: Retrospective review of a multicenter prospectively collected database. Dat...
Gender differences in the effect of adiposity on markers of cardiovascular risk...
Leal, DA; Correia-Costa, L; Moura, C; Mota, C; Correia-Costa, A; Areias, JC; Guerra, A; Afonso, AC; Azevedo, AINTRODUCTION: In the last years, evidence has started to emerge on the presence of cardiometabolic differences between genders before puberty. This study aims to evaluate if the association between obesity and markers of cardiovascular risk is different between genders in 8 to 9-year-olds. METHODS: Cross sectional study of 315 children (167 boys) aged 8-9 years old, followed in the birth cohort Generation XXI (...
Prenatal alcohol exposure affects renal function in overweight schoolchildren: ...
Correia-Costa, L; Schaefer, F; Afonso, AC; Correia, S; Guimarães, JT; Guerra, A; Barros, H; Azevedo, ABackground: Prenatal ethanol exposure has been shown to reduce nephron endowment in animal models, but the effect of alcohol during human pregnancy on postnatal kidney function has not been explored. We aim to investigate the potential association of maternal alcohol consumption during pregnancy with the offspring renal function, considering potential confounding by intrauterine growth and children’s current nu...