The purpose of this study was to determine naproxen concentrations in rat plasma samples by HPLC and to compare the bioavailability of a generic and two compounded naproxen sodium suspensions (test 1 and test 2). Analysis was run at a fl ow rate of 1.2 mL.min-1 with a mobile phase of acetonitrile: NaH2PO4 0.01 M pH 4.00 (50:50, v/v) at 280 nm, using a C18 column (150 mm x 4.6 mm, 5 μm). The calibration curve wa...
p.48-54; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-09-04T14:24:11Z No. of bitstreams: 1 JBABM-02-048.pdf: 1188444 bytes, checksum: 13bad23cb399c52a37a8ec07c39b2b48 (MD5); Approved for entry into archive by Alda Lima da Silva(sivalda@ufba.br) on 2013-09-12T17:06:42Z (GMT) No. of bitstreams: 1 JBABM-02-048.pdf: 1188444 bytes, checksum: 13bad23cb399c52a37a8ec07c39b2b48 (MD5); Made available in DSpac...