6 documents found, page 1 of 1
Rhinitis Associated with Asthma is Distinct from Rhinitis Alone: The ARIA‐MeDAL...
Bousquet, J; Melén, E; Haahtela, T; Koppelman, GH; Togias, A; Valenta, R; Akdis, CA; Czarlewski, W; Rothenberg, M; Valiulis, A; Wickman, M; Akdis, MAsthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...
Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug ...
Mamede, Ana Catarina Manjolinha; Guerra, S; Laranjo, Marta; Santos, K; Carvalho, Maria J; Carvalheiro, Tiago; Moura, P; Paiva, A; Abrantes, Ana MThe anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously results reported by our team proved that hAM is able to induce cytotoxicity and cell death in hepatocellular carcinoma (HCC), a worldwide high incident and mortal cancer. Therefore, this experimental study aime...
Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug ...
Mamede, AC; Guerra, S; Laranjo, M; Santos, K; Carvalho, MJ; Carvalheiro, T; Moura, P; Paiva, A; Abrantes, AM; Maia, CJ; Botelho, MFThe anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously results reported by our team proved that hAM is able to induce cytotoxicity and cell death in hepatocellular carcinoma (HCC), a worldwide high incident and mortal cancer. Therefore, this experimental study aime...
Selective cytotoxicity and cell death induced by human amniotic membrane in hep...
Mamede, Ana Catarina Manjolinha; Guerra, S; Laranjo, Marta; Carvalho, Maria J; Oliveira, R C; Gonçalves, A C; Alves, R; Castro, L PradoHepatocellular carcinoma (HCC) has a worldwide high incidence and mortality. For this reason, it is essential to invest in new therapies for this type of cancer. Our team already proved that human amniotic membrane (hAM) is able to inhibit the metabolic activity of several human cancer cell lines, including HCC cell lines. Taking into account the previously performed work, this experimental study aimed to inves...
Diabetes Gestacional nos Anos 2000 e 2010: Retrato de uma Sociedade?
Simões, A; Robalo, R; Gomes, G; Aleixo, F; Amaral, N; Guerra, SObjetivos: O objetivo deste trabalho foi comparar as características de mulheres com diagnóstico de diabetes gestacional, em 2 anos, separados por uma década. Tipo de estudo: Estudo retrospetivo. Local: Maternidade Dr. Alfredo da Costa. População: Grávidas vigiadas na nossa instituição com diagnóstico de diabetes gestacional nos anos de 2000 (103 mulheres) e 2010 (299 mulheres). Métodos: Foram comparados 2 grup...
Existem Diferenças Entre a Primeira e a Segunda Gravidez com Diabetes Gestacional?
Marques, C; Rocha, S; Amaral, N; Aleixo, F; Guerra, SIntrodução: As mulheres com antecedentes de Diabetes Gestacional (DG) têm um risco aumentado de recorrência em futuras gestações. Objectivo: Caracterizar a primeira e segunda gravidez com DG, na mesma mulher, e avaliar eventuais diferenças. Material e Métodos: Estudo retrospectivo de mulheres com duas gravidezes com DG que frequentaram a Consulta de Diabetes e Gravidez na nossa instituição, entre 2004 e 2010 (n...