18 documents found, page 1 of 2
DNA interactions, antitubercular and cytotoxic activity of heteroleptic CuII co...
Guerra, Wendell
DNA interactions, antitubercular and cytotoxic activity of heteroleptic Cu-II c...
Almeida, Janaina do Couto; Silva, Raphael T. C.; Zanetti, Renan D. [UNESP]; Moreira, Mariete B. [UNESP]; Portes, Marcelo C.; Polloni, LorenaMade available in DSpace on 2021-06-26T05:25:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-05; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Herein, we describe the synthesis and characterization of novel heteroleptic copper(II) complexes, [Cu(2-HNA)(phen)ClO4]center dot 1 center dot 5H(2)O I, [Cu(6-HNA)(ph...
DNA binding, cleavage, apoptosis and cytotoxicity studies of three heteroleptic...
Guerra, Wendell
Crystal structure, anti-Trypanosoma cruzi and cytotoxic activities of Cu(II) co...
Guerra, Wendell
DNA binding, cleavage, apoptosis and cytotoxicity studies of three heteroleptic...
Sousa, Luana M.; Souza, Wesley A.; Paixao, Drielly A.; Fazzi, Rodrigo B.; Tezuka, Daiane Y.; Lopes, Carla D.; Carneiro, Zumira A.Made available in DSpace on 2020-12-10T17:38:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); In this work, three nickel(II) comp...
In vitro anti-Trypanosoma cruzi activity of ternary copper(II) complexes and in...
Guerra, Wendell
In vitro anti-Trypanosoma cruzi activity of ternary copper(II) complexes and in...
Paixão, Drielly A.; Lopes, Carla D.; Carneiro, Zumira A.; Sousa, Luana M.; de Oliveira, Leticia P.; Lopes, Norberto P.; Pivatto, MarcosMade available in DSpace on 2019-10-06T16:48:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01; Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); In order to improve the previously observed antichagasic activity of Cu(II) complexes containing 2-chlorobenzhydrazide (2-CH), we report herein the synthesis and anti-Trypanosoma cruzi activity of novel copper complexes containing 2-meth...
Coordenação de metais a antibióticos como uma estratégia de combate à resistênc...
Rocha, Diego Pessoa; Pinto, Gabriel Ferreira; Ruggiero, Reinaldo; Oliveira, Carlos Alberto de; Guerra, Wendell; Fontes, Ana Paula Soares-; Antibiotic resistance has been growing at an alarming rate and consequently the arsenal of effective antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically. In this sense there is a strong need to produce new substances that not only have good spectrum of activity, but having new mechanisms of action. In this regard, this paper emphasizes the coordination of metals to antibioti...
Síntese e caracterização de novos complexos de platina (II) com ligantes deriva...
Guerra, Wendell; Fontes, Ana Paula Soares; Almeida, Mauro Vieira de; Silva, Heveline-; Platinum (II) complexes, for example, cisplatin and carboplatin, have been used as chemotherapeutic agents for the treatment of various types of cancer. Several other complexes of this metallic ion are also under clinical evaluation. This work describes the synthesis of five new platinum (II) complexes having furan and 5-nitrofuran derivatives and chloride as ligands. The compounds were characterized by NMR,...
Síntese e caracterização de um novo complexo de platina (IV) a partir de seu an...
Guerra, Wendell; Silva, Heveline; Almeida, Mauro Vieira de; Fontes, Ana Paula Soares-; In an attempt to reduce toxicity and widen the spectrum of activity of cisplatin and its analogues, much attention has been focused on designing new platinum complexes. This work reports the synthesis and characterization of novel compounds of the platinum (II) and platinum (IV) containing 2-furoic hydrazide acid and iodide as ligands. Although the prepared compounds do not present the classical structure of...