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Ramsey hunt syndrome after antimonial treatment for American Cutaneous Leishman...

Cavalcante,Melissa de Sousa Melo; Rodríguez,Karina López; Diéguez,José Alejandro Lazo; Santos,Luciana Mendes dos; Guerra,Maria das Graças Vale Barbosa

Abstract Ramsay Hunt Syndrome (RHS), also known as herpes zoster oticus, is caused by the reactivation of varicella zoster virus (VZV) in the geniculate ganglion of the facial nerve. Herein, we report a case of Ramsey Hunt Syndrome in a patient after antimonial treatment for Cutaneous Leishmaniasis. The patient presented with microvesicles grouped on an erythematous base, starting in the neck and ascending towa...

Date: 2021   |   Origin: Oasisbr

Implantable cardioverter-defibrillator prevents sudden death in patients with C...

Couceiro,Katia do Nascimento; Ortiz,Jessica Vanina; Silva,Mônica Regina Hosannah da Silva e; Sousa,Débora Raysa Teixeira de; Souza,Kenny Rodrigues de

Abstract Chagas disease (CD), with approximately 10,000 deaths annually, has become a worldwide health problem. Approximately 35% of cases may show cardiac manifestations such as arrhythmias and/or conduction disorders, heart failure, thromboembolic accidents, and sudden death. The Amazon region has long been considered a non-endemic area for CD; however, in the last decades, with an increase in the number of a...

Date: 2021   |   Origin: Oasisbr

Treatment of tegumentary leishmaniasis in two hemodialysis patients with end-st...

Petruccelli,Karla Cristina; Couceiro,Kátia Nascimento; Guerra,Maria das Graças Vale Barbosa; Vasconcelos,Zanair Soares; Brandão,Alba Regina Jorge

Abstract In this study, we present two cases of cutaneous leishmaniasis in patients with end-stage renal disease, who were treated solely with intramuscular pentamidine. In such cases, treatment implies a fine line between therapeutic efficacy and toxicity. This is suggestive of a knowledge gap; however, findings indicate that this is still the fastest and safest alternative to the treatment with antimonials. A...

Date: 2021   |   Origin: Oasisbr

Trypanosoma cruzi discrete typing unit TcIV implicated in a case of acute Chaga...

Vasconcelos,Luciene Almeida Siqueira de; Oliveira,Josué Costa; Silva Junior,Rubens Celso Andrade da; Justiniano,Silvia Cássia Brandão

Abstract Chagas disease is caused by the protozoan Trypanosoma cruzi. Seven lineages have been identified based on different molecular markers, namely TcI, TcII, TcIII, TcIV, TcV, TcVI, and TcBat. Dogs play the role of epidemiological sentinels being domestic reservoirs of T. cruzi. The aim of the current study was to report the first case of CD in a domestic dog in Manaus, Amazonas, Brazil, infected with T. cr...

Date: 2021   |   Origin: Oasisbr

Clinical and epidemiological profiles of patients with American cutaneous leish...

Melo,Maria Gabriella Nunes de; Morais,Rayana Carla Silva de; Goes,Tayná Correia de; Silva,Rômulo Pessoa e; Morais,Rômulo Freire de

Abstract INTRODUCTION: Brazil has a high number of cases of American cutaneous leishmaniasis (ACL) in the north and northeast regions. Therefore, continuous surveillance of environmental and socioeconomic factors in endemic areas is needed to develop strategic control measures. This study aimed to describe the clinical and epidemiological profiles of patients with ACL. METHODS: All patients were from the states...

Date: 2020   |   Origin: Oasisbr

Cardiac Evaluation in the Acute Phase of Chagas’ Disease with Post-Treatment Ev...

Ortiz,Jessica Vanina; Pereira,Bruna Valessa Moutinho; Couceiro,Katia do Nascimento; Silva,Monica Regina Hosannah da Silva e; Doria,Susan Smith

Abstract Background: In the past two decades, a new epidemiological profile of Chagas’ disease (CD) has been registered in the Brazilian Amazon where oral transmission has been indicated as responsible for the increase of acute cases. In the Amazonas state, five outbreaks of acute CD have been registered since 2004. The cardiac manifestations in these cases may be characterized by diffuse myocarditis, with alte...

Date: 2019   |   Origin: Oasisbr

Type 1 cardiorenal syndrome in a patient with an acute infection caused by Tryp...

Petruccelli,Karla Cristina; Tavares,Gabriel Castro; Lima,Márcio Pinheiro; Ortiz,Jessica Vanina; Brandão,Alba Regina; Couceiro,Katia do Nascimento

Abstract Cardiorenal syndrome type 1 (CRS 1) occurs when acute heart failure leads to acute kidney injury. There are several etiologies of CRS 1, including Chagas disease. Here, we present the first case report of CRS 1 in a patient with acute Chagas disease. Electrocardiography, transthoracic echocardiography, and cardiac magnetic resonance imaging showed signs of acute myocarditis. Laboratory examination reve...

Date: 2018   |   Origin: Oasisbr

Chronic Heart Disease after Treatment of Oral Acute Chagas Disease

Antunes,Andrei Fornanciari; Maduro,Simão Gonçalves; Pereira,Bruna Valessa Moutinho; Barbosa,Maria das Graças Vale; Guerra,Jorge Augusto de Oliveira

Abstract We describe the recurrence of cardiac abnormalities in a patient treated during the acute phase of Chagas disease after outpatient follow-up of 5 years.

Date: 2016   |   Origin: Oasisbr

Efficacy and safety of a single dose pentamidine (7mg/kg) for patients with cut...

Gadelha,Ellen Priscilla Nunes; Talhari,Sinésio; Guerra,Jorge Augusto de Oliveira; Neves,Leandro Ourives; Talhari,Carolina; Gontijo,Bernardo

Abstract: BACKGROUND: There have been few studies on pentamidine in the Americas; and there is no consensus regarding the dose that should be applied. OBJECTIVES: To evaluate the use of pentamidine in a single dose to treat cutaneous leishmaniasis. METHODS: Clinical trial of phase II pilot study with 20 patients. Pentamidine was used at a dose of 7 mg/kg, in a single dose. Safety and adverse effects were also a...

Date: 2015   |   Origin: Oasisbr

Polymerase chain reaction-based method for the identification of Leishmania (Vi...

Prestes,Suzane Ribeiro; Guerra,Jorge Augusto de Oliveira; Romero,Gustavo Adolfo Sierra; Magalhaes,Laylah Kelre Costa; Santana,Rosa Amelia Gonçalves

ABSTRACTINTRODUCTION: In the Americas, mucosal leishmaniasis is primarily associated with infection by Leishmania (Viannia) braziliensis. However, Leishmania (Viannia) guyanensis is another important cause of this disease in the Brazilian Amazon. In this study, we aimed at detecting Leishmaniadeoxyribonucleic acid (DNA) within paraffin-embedded fragments of mucosal tissues, and characterizing the infecting para...

Date: 2015   |   Origin: Oasisbr

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