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Amifostine reduces inflammation and protects against 5-fluorouracil-induced ora...
Barbosa, Sabrina Carneiro Melo; Pereira, Venúcia B.M.; Wong, Deysi V.T.; Santana, Ana P.M.; Lucetti, Larisse T.; Carvalho, Lucas L.Oral mucositis (OM) is a common and dose-limiting side effect of cancer treatment, including 5-fluorouracil (5-FU) andradiotherapy. The efficacy of the therapeutic measures to prevent OM is limited and disease prevention is not fully observable.Amifostine is a cytoprotective agent with a described anti-inflammatory potential. It is clinically used to reduce radiotherapy andchemotherapy-associated xerostomia. Th...
Data: 2019
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Origem: Oasisbr